ID   LAS2_MACFA              Reviewed;         322 AA.
AC   Q4R815;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Lung adenoma susceptibility protein 2 homolog;
DE   Flags: Precursor;
GN   Name=LAS2; ORFNames=QtsA-13763;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Might play a role in cell proliferation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
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DR   EMBL; AB168646; BAE00757.1; -; mRNA.
DR   AlphaFoldDB; Q4R815; -.
DR   SMR; Q4R815; -.
DR   eggNOG; ENOG502RM40; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR031587; LAS2.
DR   Pfam; PF15792; LAS2; 1.
PE   2: Evidence at transcript level;
KW   Phosphoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..31
FT                   /evidence="ECO:0000255"
FT   CHAIN           32..322
FT                   /note="Lung adenoma susceptibility protein 2 homolog"
FT                   /id="PRO_0000019562"
FT   REGION          148..175
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          228..248
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        229..248
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         161
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8IYD9"
SQ   SEQUENCE   322 AA;  36290 MW;  DCCAEE397DBEABB2 CRC64;
     MAKSKTKHRL CSRESSVSSL LASCSLSDSN SSNSDGSYHY KDKLYRSASQ ALQAYIDDFD
     LSQMYPGTST GKINIDEDFT NMSQFCNYIY KPNNAFENLD HKKHSNFISC RRQTINDIDS
     MSLTTDDLLR LPADGSFSYT YVGPSHRTNK KNKKCHGRLG SSDVEKNPNF QGPSTPVGDK
     IELLILKAKR NLEQCTEELP KSMKKDDSPC SLDKLEAERS WENIPVTFKS PIPVNSDDSP
     QQTSRAKSAT GVLEDFLNND NQSCTLSGGK HHGPVEALKQ MLFNLQAVQE RFNQNKATEP
     KEEIKQVSED DFSKLQLKER QF