ID   LAT1N_HUMAN             Reviewed;         180 AA.
AC   Q8MH63;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Putative L-type amino acid transporter 1-like protein MLAS;
DE   AltName: Full=hLAT1 3-transmembrane protein MLAS;
DE            Short=hLAT1 3TM MLAS;
GN   Name=SLC7A5P1; Synonyms=MLAS;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RX   PubMed=12009310; DOI=10.1016/s1357-2725(02)00036-5;
RA   Ito M., Takebayashi S., Okumura K., Ohkubo T., Nishio M., Kawano M.,
RA   Komada H., Ito Y., Tsurudome M.;
RT   "Up-regulated expression of a novel gene in activated human peripheral
RT   blood mononuclear cells that is a truncated paralog of the human system L-
RT   amino acid transporter 1.";
RL   Int. J. Biochem. Cell Biol. 34:1152-1163(2002).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in peripheral blood mononuclear cells and
CC       lymphoid and myeloid cell lines. {ECO:0000269|PubMed:12009310}.
CC   -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC       superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR   EMBL; AB055226; BAB97212.1; -; mRNA.
DR   AlphaFoldDB; Q8MH63; -.
DR   SMR; Q8MH63; -.
DR   iPTMnet; Q8MH63; -.
DR   PhosphoSitePlus; Q8MH63; -.
DR   BioMuta; HGNC:29458; -.
DR   DMDM; 74750867; -.
DR   jPOST; Q8MH63; -.
DR   MassIVE; Q8MH63; -.
DR   MaxQB; Q8MH63; -.
DR   PeptideAtlas; Q8MH63; -.
DR   PRIDE; Q8MH63; -.
DR   GeneCards; SLC7A5P1; -.
DR   HGNC; HGNC:29458; SLC7A5P1.
DR   neXtProt; NX_Q8MH63; -.
DR   InParanoid; Q8MH63; -.
DR   PathwayCommons; Q8MH63; -.
DR   SignaLink; Q8MH63; -.
DR   Pharos; Q8MH63; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q8MH63; protein.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015179; F:L-amino acid transmembrane transporter activity; IBA:GO_Central.
DR   InterPro; IPR002293; AA/rel_permease1.
DR   Pfam; PF13520; AA_permease_2; 1.
PE   5: Uncertain;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..180
FT                   /note="Putative L-type amino acid transporter 1-like
FT                   protein MLAS"
FT                   /id="PRO_0000348251"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        133..157
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        12..30
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   180 AA;  18779 MW;  60A302239800C3F8 CRC64;
     MAGAGPKRRA LAAPVAEEKE EAREKMLASK RADGAAPAGE GEGVTLQRNI TLLNGVAIIV
     GAIIGSGIFV TPTGVLKEAG SPGLALVMWA ACGVFSIVGA LCYAELGTTI SKSGGDYAYM
     LDVYGSLPAF LKLWIELLVI RPSSQYIVAL VFATYLLKPL FPSCPVPEEA AKLMACHCVH