ID   LATH_EQUQB              Reviewed;         205 AA.
AC   Q865V1;
DT   07-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 40.
DE   RecName: Full=Latherin;
DE   Flags: Fragment;
GN   Name=LATH;
OS   Equus quagga burchellii (Plains zebra) (Equus burchelli).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus; Equus quagga.
OX   NCBI_TaxID=89252;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Sweat gland;
RA   Fleming R.I., Holdstock N., Cooper A., Kennedy M.W.;
RT   "Latherin -- the surfactant protein from the sweat of the Chapman's/Damara
RT   zebra (Equus burchelli antiquorum).";
RL   Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Major protein in sweat, has surfactant properties.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
CC       {ECO:0000305}.
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DR   EMBL; AY226145; AAO73936.1; -; mRNA.
DR   AlphaFoldDB; Q865V1; -.
DR   SMR; Q865V1; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0050828; P:regulation of liquid surface tension; IEA:InterPro.
DR   InterPro; IPR017943; Bactericidal_perm-incr_a/b_dom.
DR   InterPro; IPR032953; Latherin.
DR   InterPro; IPR017942; Lipid-bd_serum_glycop_N.
DR   PANTHER; PTHR47015:SF3; PTHR47015:SF3; 1.
DR   Pfam; PF01273; LBP_BPI_CETP; 1.
DR   SUPFAM; SSF55394; SSF55394; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Secreted.
FT   CHAIN           <1..>205
FT                   /note="Latherin"
FT                   /id="PRO_0000089161"
FT   DISULFID        133..176
FT                   /evidence="ECO:0000250"
FT   NON_TER         1
FT   NON_TER         205
SQ   SEQUENCE   205 AA;  22290 MW;  637856CEF8B44D1D CRC64;
     QQIPPEVSSQ ITDALTQGLL DGNFLSLLNA INLEGLLNTI LDQVTGLLNI LVGPLLGSSN
     AEIKLQDARL LQLSLEFSPD SKGIDIWIPL ELSVYLKLLI LEPLTLYVRT DIRAQLQLES
     DEDGKYRLAF GHCTLLPRAI ELQTGNPLSL TVNAVLGTIE NTLGNFITED LGAGLCPTLN
     SLVSNLNLQL VNNLINLILD RANVD