ID   LAXP_EUGDY              Reviewed;          15 AA.
AC   P86708;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2010, sequence version 1.
DT   11-DEC-2019, entry version 6.
DE   RecName: Full=Laxative peptide {ECO:0000303|PubMed:20580653};
DE   Flags: Fragment;
OS   Eugenia dysenterica (Cagaita tree).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Myrteae; Eugenia group;
OC   Eugenia.
OX   NCBI_TaxID=866613;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, AND MASS SPECTROMETRY.
RC   TISSUE=Fruit flesh {ECO:0000269|PubMed:20580653};
RX   PubMed=20580653; DOI=10.1016/j.peptides.2010.05.003;
RA   Lima T.B., Silva O.N., Oliveira J.T., Vasconcelos I.M., Scalabrin F.B.,
RA   Rocha T.L., Grossi-de-Sa M.F., Silva L.P., Guadagnin R.V., Quirino B.F.,
RA   Castro C.F., Leonardecz E., Franco O.L.;
RT   "Identification of E. dysenterica laxative peptide: A novel strategy in the
RT   treatment of chronic constipation and irritable bowel syndrome.";
RL   Peptides 31:1426-1433(2010).
CC   -!- FUNCTION: Enhances intestinal motility in rats. Increases serum levels
CC       of phosphorus and magnesium ions. Has no detrimental effect on liver
CC       tissue or the mucosa of the small intestine. Has no hemolytic activity.
CC       {ECO:0000269|PubMed:20580653}.
CC   -!- MASS SPECTROMETRY: Mass=7274; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:20580653};
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PE   1: Evidence at protein level;
KW   Direct protein sequencing.
FT   PEPTIDE         1..>15
FT                   /note="Laxative peptide"
FT                   /evidence="ECO:0000269|PubMed:20580653"
FT                   /id="PRO_0000399054"
FT   NON_TER         15
FT                   /evidence="ECO:0000303|PubMed:20580653"
SQ   SEQUENCE   15 AA;  1665 MW;  0CBA4A1D9856F694 CRC64;
     DPMPAEDIVD LAYES