ID   LA_RABIT                Reviewed;          53 AA.
AC   Q04504;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Lupus La protein homolog;
DE   AltName: Full=La autoantigen homolog;
DE   AltName: Full=La ribonucleoprotein;
DE   Flags: Fragment;
GN   Name=SSB;
OS   Oryctolagus cuniculus (Rabbit).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX   NCBI_TaxID=9986;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Liver;
RX   PubMed=2476998; DOI=10.1016/0896-8411(89)90159-5;
RA   Chan E.K., Sullivan K.F.;
RT   "Sjogren's syndrome nuclear antigen B (La): cDNA cloning, structural
RT   domains, and autoepitopes.";
RL   J. Autoimmun. 2:321-327(1989).
CC   -!- FUNCTION: Binds to the 3' poly(U) terminus of nascent RNA polymerase
CC       III transcripts, protecting them from exonuclease digestion and
CC       facilitating their folding and maturation.
CC   -!- SUBUNIT: Interacts with DDX15. May interact with RUFY1 (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
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DR   EMBL; L08230; AAA31419.1; -; mRNA.
DR   AlphaFoldDB; Q04504; -.
DR   STRING; 9986.ENSOCUP00000008958; -.
DR   eggNOG; KOG4213; Eukaryota.
DR   InParanoid; Q04504; -.
DR   Proteomes; UP000001811; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR045180; La_dom_prot.
DR   PANTHER; PTHR22792; PTHR22792; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Nucleus; Phosphoprotein; Reference proteome; RNA-binding.
FT   CHAIN           <1..53
FT                   /note="Lupus La protein homolog"
FT                   /id="PRO_0000207601"
FT   REGION          1..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..43
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         8
FT                   /note="N6-acetyllysine"
FT                   /evidence="ECO:0000250|UniProtKB:P05455"
FT   MOD_RES         10
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:P05455"
FT   MOD_RES         14
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:P05455"
FT   NON_TER         1
SQ   SEQUENCE   53 AA;  5837 MW;  8F926266CCD4C92D CRC64;
     GKVEFQGKKT KFDSDDERNE NGAAGPVKRA REETDKEEPA SKQQKTENGA GDQ