LBD15_ARATH
ID LBD15_ARATH Reviewed; 224 AA.
AC Q8L5T5; A0MES9; B7XG65; O22888; Q1PEV4;
DT 28-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT 28-MAR-2003, sequence version 2.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=LOB domain-containing protein 15;
DE AltName: Full=ASYMMETRIC LEAVES 2-like protein 11;
DE Short=AS2-like protein 11;
GN Name=LBD15; Synonyms=ASL11; OrderedLocusNames=At2g40470; ORFNames=T2P4.18;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=12068116; DOI=10.1104/pp.010926;
RA Shuai B., Reynaga-Pena C.G., Springer P.S.;
RT "The LATERAL ORGAN BOUNDARIES gene defines a novel, plant-specific gene
RT family.";
RL Plant Physiol. 129:747-761(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=19154202; DOI=10.1111/j.1365-313x.2009.03797.x;
RA Matsumura Y., Iwakawa H., Machida Y., Machida C.;
RT "Characterization of genes in the ASYMMETRIC LEAVES2/LATERAL ORGAN
RT BOUNDARIES (AS2/LOB) family in Arabidopsis thaliana, and functional and
RT molecular comparisons between AS2 and other family members.";
RL Plant J. 58:525-537(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
RN [8]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12040093; DOI=10.1093/pcp/pcf077;
RA Iwakawa H., Ueno Y., Semiarti E., Onouchi H., Kojima S., Tsukaya H.,
RA Hasebe M., Soma T., Ikezaki M., Machida C., Machida Y.;
RT "The ASYMMETRIC LEAVES2 gene of Arabidopsis thaliana, required for
RT formation of a symmetric flat leaf lamina, encodes a member of a novel
RT family of proteins characterized by cysteine repeats and a leucine
RT zipper.";
RL Plant Cell Physiol. 43:467-478(2002).
CC -!- INTERACTION:
CC Q8L5T5; Q9C9L2: TCP15; NbExp=3; IntAct=EBI-2356227, EBI-4426144;
CC -!- TISSUE SPECIFICITY: Expressed in young shoots, roots, stems, leaves and
CC flowers. {ECO:0000269|PubMed:12068116}.
CC -!- SIMILARITY: Belongs to the LOB domain-containing protein family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK28530.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AF447889; AAL38034.1; -; mRNA.
DR EMBL; AB473844; BAH10555.1; -; mRNA.
DR EMBL; AC002336; AAB87589.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09834.1; -; Genomic_DNA.
DR EMBL; AY088856; AAM67163.1; -; mRNA.
DR EMBL; DQ446613; ABE65897.1; -; mRNA.
DR EMBL; DQ653051; ABK28530.1; ALT_SEQ; mRNA.
DR EMBL; BT025288; ABF19041.1; -; mRNA.
DR PIR; H84829; H84829.
DR RefSeq; NP_565933.1; NM_129608.3.
DR AlphaFoldDB; Q8L5T5; -.
DR SMR; Q8L5T5; -.
DR BioGRID; 3979; 10.
DR IntAct; Q8L5T5; 10.
DR STRING; 3702.AT2G40470.1; -.
DR PaxDb; Q8L5T5; -.
DR PRIDE; Q8L5T5; -.
DR ProteomicsDB; 250733; -.
DR EnsemblPlants; AT2G40470.1; AT2G40470.1; AT2G40470.
DR GeneID; 818641; -.
DR Gramene; AT2G40470.1; AT2G40470.1; AT2G40470.
DR KEGG; ath:AT2G40470; -.
DR Araport; AT2G40470; -.
DR TAIR; locus:2061828; AT2G40470.
DR eggNOG; ENOG502QUQH; Eukaryota.
DR HOGENOM; CLU_058353_0_0_1; -.
DR InParanoid; Q8L5T5; -.
DR OMA; RRHIMGS; -.
DR OrthoDB; 1317613at2759; -.
DR PhylomeDB; Q8L5T5; -.
DR PRO; PR:Q8L5T5; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8L5T5; baseline and differential.
DR Genevisible; Q8L5T5; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0010628; P:positive regulation of gene expression; IDA:TAIR.
DR GO; GO:1905177; P:tracheary element differentiation; IMP:TAIR.
DR InterPro; IPR004883; LOB.
DR Pfam; PF03195; LOB; 1.
DR PROSITE; PS50891; LOB; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..224
FT /note="LOB domain-containing protein 15"
FT /id="PRO_0000132266"
FT DOMAIN 44..145
FT /note="LOB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00291"
FT REGION 171..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 180..195
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 114
FT /note="R -> K (in Ref. 5; AAM67163)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 224 AA; 24660 MW; 2458B44E0CFDDAC2 CRC64;
MSRERERFEE IGKKIKREAD AWPHQMAGIR RPMSGPPGTL NTITPCAACK LLRRRCAQEC
PFSPYFSPHE PHKFASVHKV FGASNVSKML MEVPESQRAD AANSLVYEAN VRLRDPVYGC
MGAISALQQQ VQALQAELTA VRSEILKYKQ REAVATLIVP SNSQVAGFHN SGGVSVIAPP
PQRPTTPPQP TTAHPPSPSS CVFSQPTTRD LEYGNIESEN NYFG