LBD30_ARATH
ID LBD30_ARATH Reviewed; 228 AA.
AC O81323; A0MF43; B7XG73; Q1PED1;
DT 17-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=LOB domain-containing protein 30;
DE AltName: Full=ASYMMETRIC LEAVES 2-like protein 19;
DE Short=AS2-like protein 19;
GN Name=LBD30; Synonyms=ASL19; OrderedLocusNames=At4g00220; ORFNames=F6N15.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, GENE FAMILY, AND
RP NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=12068116; DOI=10.1104/pp.010926;
RA Shuai B., Reynaga-Pena C.G., Springer P.S.;
RT "The LATERAL ORGAN BOUNDARIES gene defines a novel, plant-specific gene
RT family.";
RL Plant Physiol. 129:747-761(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=19154202; DOI=10.1111/j.1365-313x.2009.03797.x;
RA Matsumura Y., Iwakawa H., Machida Y., Machida C.;
RT "Characterization of genes in the ASYMMETRIC LEAVES2/LATERAL ORGAN
RT BOUNDARIES (AS2/LOB) family in Arabidopsis thaliana, and functional and
RT molecular comparisons between AS2 and other family members.";
RL Plant J. 58:525-537(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12040093; DOI=10.1093/pcp/pcf077;
RA Iwakawa H., Ueno Y., Semiarti E., Onouchi H., Kojima S., Tsukaya H.,
RA Hasebe M., Soma T., Ikezaki M., Machida C., Machida Y.;
RT "The ASYMMETRIC LEAVES2 gene of Arabidopsis thaliana, required for
RT formation of a symmetric flat leaf lamina, encodes a member of a novel
RT family of proteins characterized by cysteine repeats and a leucine
RT zipper.";
RL Plant Cell Physiol. 43:467-478(2002).
RN [8]
RP FUNCTION, AND TISSUE SPECIFICITY.
RX PubMed=19088331; DOI=10.1105/tpc.108.061796;
RA Soyano T., Thitamadee S., Machida Y., Chua N.-H.;
RT "ASYMMETRIC LEAVES2-LIKE19/LATERAL ORGAN BOUNDARIES DOMAIN30 and
RT ASL20/LBD18 regulate tracheary element differentiation in Arabidopsis.";
RL Plant Cell 20:3359-3373(2008).
CC -!- FUNCTION: Involved in the positive regulation of tracheary element (TE)
CC differentiation. Involved in a positive feedback loop that maintains or
CC promotes NAC030/VND7 expression that regulates TE differentiation-
CC related genes. {ECO:0000269|PubMed:19088331}.
CC -!- INTERACTION:
CC O81323; Q9SHE9: LBD4; NbExp=3; IntAct=EBI-15201724, EBI-4445715;
CC O81323; Q93Z00: TCP14; NbExp=3; IntAct=EBI-15201724, EBI-4424563;
CC -!- TISSUE SPECIFICITY: Expressed in roots, stems, leaves and flowers
CC (PubMed:12068116). Expressed in vascular tissues of hypocotyls, leaves,
CC roots, developing floral organs and siliques (PubMed:19088331).
CC {ECO:0000269|PubMed:12068116, ECO:0000269|PubMed:19088331}.
CC -!- MISCELLANEOUS: Plants over-expressing LBD30 have a dwarf and bushy
CC phenotype, with short petioles, curled downward leaves, ectopic shoots
CC from the adaxial side of cotyledons, shrunken root tips and
CC disorganized columella cells. {ECO:0000269|PubMed:19088331}.
CC -!- SIMILARITY: Belongs to the LOB domain-containing protein family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK28616.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AF432232; AAL27613.1; -; mRNA.
DR EMBL; AB473852; BAH10563.1; -; mRNA.
DR EMBL; AF069299; AAC19300.1; -; Genomic_DNA.
DR EMBL; AL161471; CAB80780.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE81839.1; -; Genomic_DNA.
DR EMBL; DQ446787; ABE66037.1; -; mRNA.
DR EMBL; DQ653168; ABK28616.1; ALT_SEQ; mRNA.
DR EMBL; BT026407; ABH04514.1; -; mRNA.
DR PIR; T01350; T01350.
DR RefSeq; NP_191933.1; NM_116239.4.
DR AlphaFoldDB; O81323; -.
DR SMR; O81323; -.
DR BioGRID; 13375; 11.
DR IntAct; O81323; 6.
DR STRING; 3702.AT4G00220.1; -.
DR PaxDb; O81323; -.
DR PRIDE; O81323; -.
DR ProteomicsDB; 250726; -.
DR EnsemblPlants; AT4G00220.1; AT4G00220.1; AT4G00220.
DR GeneID; 828084; -.
DR Gramene; AT4G00220.1; AT4G00220.1; AT4G00220.
DR KEGG; ath:AT4G00220; -.
DR Araport; AT4G00220; -.
DR TAIR; locus:2126881; AT4G00220.
DR eggNOG; ENOG502QR68; Eukaryota.
DR HOGENOM; CLU_058353_3_5_1; -.
DR InParanoid; O81323; -.
DR OMA; YMPMTTE; -.
DR OrthoDB; 1304135at2759; -.
DR PhylomeDB; O81323; -.
DR PRO; PR:O81323; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; O81323; baseline and differential.
DR Genevisible; O81323; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0009755; P:hormone-mediated signaling pathway; IBA:GO_Central.
DR GO; GO:0010199; P:organ boundary specification between lateral organs and the meristem; IMP:TAIR.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IBA:GO_Central.
DR GO; GO:0010089; P:xylem development; IMP:TAIR.
DR InterPro; IPR004883; LOB.
DR Pfam; PF03195; LOB; 1.
DR PROSITE; PS50891; LOB; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..228
FT /note="LOB domain-containing protein 30"
FT /id="PRO_0000132281"
FT DOMAIN 16..118
FT /note="LOB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00291"
FT REGION 188..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 211..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 228 AA; 23968 MW; CAE3F2DA4C78A209 CRC64;
MSSSGNPSSS SGGGGGPCGA CKFLRRKCVA GCIFAPYFDS EQGAAHFAAV HKVFGASNVS
KLLHHVPEHK RPDAVVSICF EAQARLRDPI YGCVSHIVSL QQQVVSLQTE LSYLQAHLAT
LELPQPQPPQ VPVSSSGSLQ ALSITDLPTI SPSVYDLSSI FEPVMSSTWA MQQQPRPSDH
LFGVPSSSNM GGGGELQALA REFIHGGQMP AQPSPGTSGS ASSVIKRE
