LBD4_ARATH
ID LBD4_ARATH Reviewed; 172 AA.
AC Q9SHE9; B7XG60; Q6DBF5;
DT 28-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=LOB domain-containing protein 4;
DE AltName: Full=ASYMMETRIC LEAVES 2-like protein 6;
DE Short=AS2-like protein 6;
GN Name=LBD4; Synonyms=ASL6; OrderedLocusNames=At1g31320; ORFNames=T19E23.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=19154202; DOI=10.1111/j.1365-313x.2009.03797.x;
RA Matsumura Y., Iwakawa H., Machida Y., Machida C.;
RT "Characterization of genes in the ASYMMETRIC LEAVES2/LATERAL ORGAN
RT BOUNDARIES (AS2/LOB) family in Arabidopsis thaliana, and functional and
RT molecular comparisons between AS2 and other family members.";
RL Plant J. 58:525-537(2009).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12068116; DOI=10.1104/pp.010926;
RA Shuai B., Reynaga-Pena C.G., Springer P.S.;
RT "The LATERAL ORGAN BOUNDARIES gene defines a novel, plant-specific gene
RT family.";
RL Plant Physiol. 129:747-761(2002).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12040093; DOI=10.1093/pcp/pcf077;
RA Iwakawa H., Ueno Y., Semiarti E., Onouchi H., Kojima S., Tsukaya H.,
RA Hasebe M., Soma T., Ikezaki M., Machida C., Machida Y.;
RT "The ASYMMETRIC LEAVES2 gene of Arabidopsis thaliana, required for
RT formation of a symmetric flat leaf lamina, encodes a member of a novel
RT family of proteins characterized by cysteine repeats and a leucine
RT zipper.";
RL Plant Cell Physiol. 43:467-478(2002).
CC -!- INTERACTION:
CC Q9SHE9; Q94ID6: ERF12; NbExp=3; IntAct=EBI-4445715, EBI-4446727;
CC Q9SHE9; Q9AT61: LBD13; NbExp=4; IntAct=EBI-4445715, EBI-4432427;
CC Q9SHE9; P59467: LBD23; NbExp=3; IntAct=EBI-4445715, EBI-15193845;
CC Q9SHE9; O81323: LBD30; NbExp=3; IntAct=EBI-4445715, EBI-15201724;
CC Q9SHE9; Q9FML4: LOB; NbExp=3; IntAct=EBI-4445715, EBI-15194891;
CC -!- TISSUE SPECIFICITY: Expressed in young shoots, roots, stems, leaves and
CC flowers. {ECO:0000269|PubMed:12068116}.
CC -!- SIMILARITY: Belongs to the LOB domain-containing protein family.
CC {ECO:0000305}.
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DR EMBL; AB473839; BAH10550.1; -; mRNA.
DR EMBL; AC007654; AAF24588.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31341.1; -; Genomic_DNA.
DR EMBL; BT015067; AAT71939.1; -; mRNA.
DR EMBL; BT015665; AAU15164.1; -; mRNA.
DR PIR; B86439; B86439.
DR RefSeq; NP_174417.1; NM_102870.3.
DR AlphaFoldDB; Q9SHE9; -.
DR SMR; Q9SHE9; -.
DR BioGRID; 25255; 11.
DR IntAct; Q9SHE9; 10.
DR STRING; 3702.AT1G31320.1; -.
DR PaxDb; Q9SHE9; -.
DR PRIDE; Q9SHE9; -.
DR ProteomicsDB; 238557; -.
DR EnsemblPlants; AT1G31320.1; AT1G31320.1; AT1G31320.
DR GeneID; 840020; -.
DR Gramene; AT1G31320.1; AT1G31320.1; AT1G31320.
DR KEGG; ath:AT1G31320; -.
DR Araport; AT1G31320; -.
DR TAIR; locus:2197500; AT1G31320.
DR eggNOG; ENOG502R4HI; Eukaryota.
DR HOGENOM; CLU_058353_5_2_1; -.
DR InParanoid; Q9SHE9; -.
DR OMA; FSHMDIV; -.
DR OrthoDB; 1352113at2759; -.
DR PhylomeDB; Q9SHE9; -.
DR PRO; PR:Q9SHE9; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SHE9; baseline and differential.
DR Genevisible; Q9SHE9; AT.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0010087; P:phloem or xylem histogenesis; IDA:TAIR.
DR InterPro; IPR004883; LOB.
DR Pfam; PF03195; LOB; 1.
DR PROSITE; PS50891; LOB; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..172
FT /note="LOB domain-containing protein 4"
FT /id="PRO_0000132255"
FT DOMAIN 12..113
FT /note="LOB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00291"
FT REGION 125..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 126..151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 172 AA; 18697 MW; 8411DCF71F1F7097 CRC64;
MKESSRKQGA ASPCAACKLL RRRCAQDCVF SPYFPADEPQ KFANVHRVFG ASNVNKMLQE
LPIHQRGDAV SSMVYEANAR VRDPVYGCVG AISSLQQQID VLQAQLALAQ AEVVHLRVRQ
STNFPGHGLC PDSPSSSGSP SSKQVSPQDN KGMFSHMDIV DEASLGESMW SC
