ID   LBH_XENLA               Reviewed;         102 AA.
AC   Q91715;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Protein LBH;
DE   AltName: Full=Cleavage 2 protein;
DE   AltName: Full=XLCL2;
GN   Name=lbh; Synonyms=cl2;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2358121; DOI=10.1016/0012-1606(90)90070-y;
RA   Paris J., Philippe M.;
RT   "Poly(A) metabolism and polysomal recruitment of maternal mRNAs during
RT   early Xenopus development.";
RL   Dev. Biol. 140:221-224(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   DEVELOPMENTAL STAGE.
RX   PubMed=15935340; DOI=10.1016/j.ydbio.2005.04.020;
RA   Takada H., Hattori D., Kitayama A., Ueno N., Taira M.;
RT   "Identification of target genes for the Xenopus Hes-related protein XHR1, a
RT   prepattern factor specifying the midbrain-hindbrain boundary.";
RL   Dev. Biol. 283:253-267(2005).
CC   -!- FUNCTION: Transcriptional activator. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in anterior neural plate.
CC       {ECO:0000269|PubMed:15935340}.
CC   -!- SIMILARITY: Belongs to the LBH family. {ECO:0000305}.
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DR   EMBL; Z14122; CAA78495.1; -; mRNA.
DR   EMBL; BC068648; AAH68648.1; -; mRNA.
DR   PIR; S52241; S52241.
DR   RefSeq; NP_001081507.1; NM_001088038.1.
DR   AlphaFoldDB; Q91715; -.
DR   MaxQB; Q91715; -.
DR   GeneID; 397879; -.
DR   KEGG; xla:397879; -.
DR   CTD; 397879; -.
DR   Xenbase; XB-GENE-5945566; lbh.L.
DR   OrthoDB; 1541774at2759; -.
DR   Proteomes; UP000186698; Chromosome 5L.
DR   Bgee; 397879; Expressed in spleen and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR013294; LBH.
DR   InterPro; IPR038990; LBH_dom.
DR   InterPro; IPR042945; LBH_dom_prot.
DR   PANTHER; PTHR14987; PTHR14987; 1.
DR   Pfam; PF15317; Lbh; 1.
DR   PIRSF; PIRSF008130; LBH; 1.
DR   PRINTS; PR01881; LBHPROTEIN.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..102
FT                   /note="Protein LBH"
FT                   /id="PRO_0000324806"
FT   DOMAIN          18..101
FT                   /note="LBH"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   102 AA;  11811 MW;  05ACC36AAB85A6AD CRC64;
     MSVFYPIHCT DYLRSAEMTE VIMNTQSMDE IGLSPRKDSY QIFPDPSDFE RCCKLKDRLP
     SIVVEPTEGD VESGELRWPP EEFVVDEDKE GTCDQTKKEN EQ