LBH_XENTR
ID LBH_XENTR Reviewed; 102 AA.
AC Q5M7L2; Q28FB6;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-2005, sequence version 1.
DT 03-AUG-2022, entry version 66.
DE RecName: Full=Protein LBH;
GN Name=lbh; ORFNames=TEgg141o05.1;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Egg;
RG Sanger Xenopus tropicalis EST/cDNA project;
RL Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Transcriptional activator. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LBH family. {ECO:0000305}.
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DR EMBL; CR762050; CAJ81937.1; -; mRNA.
DR EMBL; BC088576; AAH88576.1; -; mRNA.
DR RefSeq; NP_001011389.1; NM_001011389.1.
DR AlphaFoldDB; Q5M7L2; -.
DR STRING; 8364.ENSXETP00000017424; -.
DR PaxDb; Q5M7L2; -.
DR DNASU; 496858; -.
DR GeneID; 496858; -.
DR KEGG; xtr:496858; -.
DR CTD; 81606; -.
DR Xenbase; XB-GENE-5945476; lbh.
DR eggNOG; ENOG502S1QG; Eukaryota.
DR InParanoid; Q5M7L2; -.
DR OrthoDB; 1541774at2759; -.
DR Proteomes; UP000008143; Chromosome 5.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000007948; Expressed in heart and 19 other tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR013294; LBH.
DR InterPro; IPR038990; LBH_dom.
DR InterPro; IPR042945; LBH_dom_prot.
DR PANTHER; PTHR14987; PTHR14987; 1.
DR Pfam; PF15317; Lbh; 1.
DR PIRSF; PIRSF008130; LBH; 1.
DR PRINTS; PR01881; LBHPROTEIN.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..102
FT /note="Protein LBH"
FT /id="PRO_0000324807"
FT DOMAIN 18..101
FT /note="LBH"
FT /evidence="ECO:0000255"
FT REGION 66..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..102
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 55
FT /note="L -> M (in Ref. 1; CAJ81937)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 102 AA; 11807 MW; B83CC5B2674AA561 CRC64;
MSVFYPIHCT DYLRSAEMTE VIMNTQPMDE IGLSPRKDSY QIFPDPSDFE RCCKLKDRLP
SIVVEPTEGD VESGELRWPP EEFVVDEDKE GSCDQTKKEN EQ