ID   LBTA_DIESC              Reviewed;         124 AA.
AC   A1XI29;
DT   12-AUG-2020, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 22.
DE   RecName: Full=Putative C(50) carotenoid beta-cyclase subunit A {ECO:0000305};
DE            EC=5.5.1.- {ECO:0000305|PubMed:17008032};
GN   Name=lbtA {ECO:0000303|PubMed:17008032};
OS   Dietzia sp. (strain CQ4).
OC   Bacteria; Actinobacteria; Corynebacteriales; Dietziaceae; Dietzia;
OC   unclassified Dietzia.
OX   NCBI_TaxID=370437;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, PATHWAY, AND SUBUNIT.
RC   STRAIN=CQ4;
RX   PubMed=17008032; DOI=10.1016/j.gene.2006.08.006;
RA   Tao L., Yao H., Cheng Q.;
RT   "Genes from a Dietzia sp. for synthesis of C40 and C50 beta-cyclic
RT   carotenoids.";
RL   Gene 386:90-97(2007).
CC   -!- FUNCTION: Involved in the biosynthesis of C(50) beta-cyclic carotenoids
CC       (PubMed:17008032). May have C(50) carotenoid beta-cyclase activity and
CC       produce the C(50) beta-cyclic carotenoid C.p.450 from the C(50)
CC       carotenoid dihydrobisanhydrobacterioruberin (DH-BABR) (Probable).
CC       {ECO:0000269|PubMed:17008032, ECO:0000305|PubMed:17008032}.
CC   -!- PATHWAY: Carotenoid biosynthesis. {ECO:0000269|PubMed:17008032}.
CC   -!- SUBUNIT: May form a complex with LbtBC. {ECO:0000305|PubMed:17008032}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the lycopene beta-cyclase family. {ECO:0000305}.
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DR   EMBL; DQ369754; ABD24401.1; -; Genomic_DNA.
DR   AlphaFoldDB; A1XI29; -.
DR   KEGG; ag:ABD24401; -.
DR   BioCyc; MetaCyc:MON-20368; -.
DR   BRENDA; 2.5.1.150; 16303.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016872; F:intramolecular lyase activity; IEA:InterPro.
DR   GO; GO:0045436; F:lycopene beta cyclase activity; IEA:UniProt.
DR   GO; GO:0016120; P:carotene biosynthetic process; IEA:UniProt.
DR   GO; GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR017825; Lycopene_cyclase_dom.
DR   TIGRFAMs; TIGR03462; CarR_dom_SF; 1.
PE   1: Evidence at protein level;
KW   Carotenoid biosynthesis; Cell membrane; Isomerase; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..124
FT                   /note="Putative C(50) carotenoid beta-cyclase subunit A"
FT                   /id="PRO_0000450596"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   124 AA;  13367 MW;  399FE5D7267658FD CRC64;
     MIGLSYLLVQ VVSFAGILVI DHRWKLAAFR APAAAALAVT ASVALLLTWD VLGVRSGVFF
     RGQTDFMTGL LVAPEIPFEE VVFLAFLSHL ALVCAAGVSR AVDHARDSRA ARASRPSRMT
     GERR