ID   LCA5L_BOVIN             Reviewed;         670 AA.
AC   A7E3D8;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 2.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Lebercilin-like protein;
DE   AltName: Full=Leber congenital amaurosis 5-like protein;
GN   Name=LCA5L {ECO:0000250|UniProtKB:O95447};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford;
RX   PubMed=19390049; DOI=10.1126/science.1169588;
RG   The bovine genome sequencing and analysis consortium;
RT   "The genome sequence of taurine cattle: a window to ruminant biology and
RT   evolution.";
RL   Science 324:522-528(2009).
RN   [2] {ECO:0000305, ECO:0000312|EMBL:AAI51816.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-401.
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LCA5 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI51816.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AAFC03010727; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC151815; AAI51816.1; ALT_SEQ; mRNA.
DR   RefSeq; NP_001181997.1; NM_001195068.1.
DR   AlphaFoldDB; A7E3D8; -.
DR   SMR; A7E3D8; -.
DR   STRING; 9913.ENSBTAP00000054161; -.
DR   PaxDb; A7E3D8; -.
DR   PRIDE; A7E3D8; -.
DR   Ensembl; ENSBTAT00000064834; ENSBTAP00000054161; ENSBTAG00000030993.
DR   GeneID; 781766; -.
DR   KEGG; bta:781766; -.
DR   CTD; 150082; -.
DR   VEuPathDB; HostDB:ENSBTAG00000030993; -.
DR   VGNC; VGNC:30808; LCA5L.
DR   eggNOG; ENOG502QQSE; Eukaryota.
DR   GeneTree; ENSGT00560000077266; -.
DR   HOGENOM; CLU_026861_0_0_1; -.
DR   InParanoid; A7E3D8; -.
DR   OMA; QIMVKHQ; -.
DR   OrthoDB; 461316at2759; -.
DR   TreeFam; TF323306; -.
DR   Proteomes; UP000009136; Chromosome 1.
DR   Bgee; ENSBTAG00000030993; Expressed in spermatid and 25 other tissues.
DR   GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR   GO; GO:0042073; P:intraciliary transport; IBA:GO_Central.
DR   InterPro; IPR026188; Lebercilin-like.
DR   InterPro; IPR028933; Lebercilin_dom.
DR   PANTHER; PTHR16650; PTHR16650; 1.
DR   Pfam; PF15619; Lebercilin; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..670
FT                   /note="Lebercilin-like protein"
FT                   /id="PRO_0000331227"
FT   REGION          1..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          373..399
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          413..453
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          145..335
FT                   /evidence="ECO:0000255"
FT   COILED          418..468
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        20..63
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        418..438
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   670 AA;  76371 MW;  43B7EFEA1C3077C5 CRC64;
     MSLAGPTETN LGGHFPGTAV ENGGSSSKRE SSSPGFPRNS NASDKSVDYS RSRCSCRSPS
     SHYDYSEDFL SACSETTARN NYLEKPTVKE KKEKKKYNVS KISQLKGQKE ISVRKKHSWN
     VPFLNSQISV AAQRRDAMIH RILSARLHKI KELKNELADL HHKAEATVIE NQFLKQVQLK
     HLKAIGKYEN SQNNLPQIMA KHQNEVKNLR QLLRKSQGKE RATSRKLREM DGELLRTKDA
     LQALQKISEE NNLPEREELT QRLSILTAKM EANDKKIQDL EKQLRLNNKA FTRQLTFENR
     KTLAAQAATK TLQMEIKHLQ QKLKEKDREL EIRNIYSNRI VGNLHDKEDY PKVSSTKSVQ
     ADRRSFPFIS MRHQETQKSE DVASWTTKSK KTTGNNGHKE KSIEIIHAMP PCITKLPNQE
     DSKRKYEDLS KEEQHLEAQP SLKNTGQQRY RTENQEKKIT LVKEEQELPP KRIEVIHPEG
     EGGQEDDTEK YKFKRSPEIS DMGDMPDKNA APHIKIPFRQ RKHYSFTEAI ENLHHGLPAS
     GGLANAGSTR YPHSTGKHHS HSEEMKLEHP AIAYEPSFAK SYRTKAKDTT FREKKSNLME
     ELFGSDYVLK NNQTSTTVMK EPEETLQSTK IHHLPPSQAS ASNAFGDSGV TVVNSIKSSS
     PTEGNRKIII