ID   LCCB_LEUCA              Reviewed;          61 AA.
AC   Q53446;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Bacteriocin leucocin-B;
DE   AltName: Full=Leucocin B-Ta11a;
DE   Flags: Precursor;
OS   Leuconostoc carnosum.
OG   Plasmid 8.9-MDa.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Leuconostoc.
OX   NCBI_TaxID=1252;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Ta11a;
RX   PubMed=7765496; DOI=10.1007/bf01570155;
RA   Felix J.V., Papathanasopoulos M.A., Smith A.A., von Holy A., Hastings J.W.;
RT   "Characterization of leucocin B-Ta11a: a bacteriocin from Leuconostoc
RT   carnosum Ta11a isolated from meat.";
RL   Curr. Microbiol. 29:207-212(1994).
CC   -!- FUNCTION: Active against L.monocytogenes and several lactic acid
CC       bacteria.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the bacteriocin class IIA/YGNGV family.
CC       {ECO:0000305}.
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DR   EMBL; S72922; AAC60488.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q53446; -.
DR   SMR; Q53446; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005186; F:pheromone activity; IEA:InterPro.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.130; -; 1.
DR   InterPro; IPR002633; Bacteriocin_IIa.
DR   InterPro; IPR023384; Bacteriocin_IIa_CS.
DR   InterPro; IPR023388; Bacteriocin_IIa_dom_sf.
DR   InterPro; IPR004288; Competence_ComC.
DR   Pfam; PF01721; Bacteriocin_II; 1.
DR   Pfam; PF03047; ComC; 1.
DR   PROSITE; PS60030; BACTERIOCIN_IIA; 1.
PE   3: Inferred from homology;
KW   Antibiotic; Antimicrobial; Bacteriocin; Disulfide bond; Plasmid; Secreted.
FT   PROPEP          1..24
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000002740"
FT   CHAIN           25..61
FT                   /note="Bacteriocin leucocin-B"
FT                   /id="PRO_0000002741"
FT   DISULFID        33..38
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   61 AA;  6568 MW;  AC405015D86C0EA4 CRC64;
     MNNMKSADNY QQLDNNALEQ VVGGKYYGNG VHCTKSGCSV NWGEAFSAGV HRLANGGNGF
     W