ID   LCCC_LEUME              Reviewed;          43 AA.
AC   P81053;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   17-JAN-2003, sequence version 2.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Bacteriocin leucocin-C;
OS   Leuconostoc mesenteroides.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Leuconostoc.
OX   NCBI_TaxID=1245;
RN   [1]
RP   PROTEIN SEQUENCE, AND MASS SPECTROMETRY.
RX   PubMed=12127968; DOI=10.1016/s0006-291x(02)00769-6;
RA   Fimland G., Sletten K., Nissen-Meyer J.;
RT   "The complete amino acid sequence of the pediocin-like antimicrobial
RT   peptide leucocin C.";
RL   Biochem. Biophys. Res. Commun. 295:826-827(2002).
RN   [2]
RP   PROTEIN SEQUENCE OF 1-36.
RC   STRAIN=TA33a;
RX   PubMed=9611809; DOI=10.1099/00221287-144-5-1343;
RA   Papathanasopoulos M.A., Dykes G.A., Revol-Junelles A.-M., Delfour A.,
RA   von Holy A., Hastings J.W.;
RT   "Sequence and structural relationships of leucocins A-, B- and C-TA33a from
RT   Leuconostoc mesenteroides TA33a.";
RL   Microbiology 144:1343-1348(1998).
CC   -!- FUNCTION: Inhibits a wide spectrum of lactic acid bacteria.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- MASS SPECTROMETRY: Mass=4595; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:12127968};
CC   -!- SIMILARITY: Belongs to the bacteriocin class IIA/YGNGV family.
CC       {ECO:0000305}.
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DR   AlphaFoldDB; P81053; -.
DR   SMR; P81053; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.5.130; -; 1.
DR   InterPro; IPR002633; Bacteriocin_IIa.
DR   InterPro; IPR023384; Bacteriocin_IIa_CS.
DR   InterPro; IPR023388; Bacteriocin_IIa_dom_sf.
DR   Pfam; PF01721; Bacteriocin_II; 1.
DR   PROSITE; PS60030; BACTERIOCIN_IIA; 1.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Bacteriocin; Direct protein sequencing;
KW   Disulfide bond; Secreted.
FT   CHAIN           1..43
FT                   /note="Bacteriocin leucocin-C"
FT                   /id="PRO_0000110575"
FT   DISULFID        9..14
FT                   /evidence="ECO:0000250"
FT   CONFLICT        22
FT                   /note="W -> A (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   43 AA;  4598 MW;  926382483FBE65C3 CRC64;
     KNYGNGVHCT KKGCSVDWGY AWTNIANNSV MNGLTGGNAG WHN