ID   LCGA_LACLL              Reviewed;          39 AA.
AC   P36961; Q9R5J1;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Bacteriocin lactococcin-G subunit alpha;
OS   Lactococcus lactis subsp. lactis (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=1360;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=LMG 2081;
RX   PubMed=1512201; DOI=10.1128/jb.174.17.5686-5692.1992;
RA   Nissen-Meyer J., Holo H., Havarstein L.S., Sletten K., Nes I.F.;
RT   "A novel lactococcal bacteriocin whose activity depends on the
RT   complementary action of two peptides.";
RL   J. Bacteriol. 174:5686-5692(1992).
CC   -!- FUNCTION: Kills Lactococci.
CC   -!- SUBUNIT: Bacteriocin activity requires interaction of alpha and beta
CC       peptides in a molar ratio of 7:1 or 8:1 respectively.
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DR   PIR; A44918; A44918.
DR   PDB; 2JPJ; NMR; -; A=1-39.
DR   PDB; 2JPL; NMR; -; A=1-39.
DR   PDBsum; 2JPJ; -.
DR   PDBsum; 2JPL; -.
DR   AlphaFoldDB; P36961; -.
DR   SMR; P36961; -.
DR   TCDB; 1.C.25.1.1; the lactococcin g (lactococcin g) family.
DR   EvolutionaryTrace; P36961; -.
DR   GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   InterPro; IPR012950; Alpha_enterocin/lactococcin.
DR   Pfam; PF08129; Antimicrobial17; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Antibiotic; Antimicrobial; Bacteriocin;
KW   Direct protein sequencing.
FT   PEPTIDE         1..39
FT                   /note="Bacteriocin lactococcin-G subunit alpha"
FT                   /id="PRO_0000044640"
FT   HELIX           3..21
FT                   /evidence="ECO:0007829|PDB:2JPJ"
FT   HELIX           26..34
FT                   /evidence="ECO:0007829|PDB:2JPJ"
FT   HELIX           35..37
FT                   /evidence="ECO:0007829|PDB:2JPJ"
SQ   SEQUENCE   39 AA;  4346 MW;  7ED3FEBA65AA2659 CRC64;
     GTWDDIGQGI GRVAYWVGKA MGNMSDVNQA SRINRKKKH