LCGB_LACLL
ID LCGB_LACLL Reviewed; 35 AA.
AC P36962;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 25-MAY-2022, entry version 52.
DE RecName: Full=Bacteriocin lactococcin-G subunit beta;
OS Lactococcus lactis subsp. lactis (Streptococcus lactis).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus.
OX NCBI_TaxID=1360;
RN [1]
RP PROTEIN SEQUENCE.
RC STRAIN=LMG 2081;
RX PubMed=1512201; DOI=10.1128/jb.174.17.5686-5692.1992;
RA Nissen-Meyer J., Holo H., Havarstein L.S., Sletten K., Nes I.F.;
RT "A novel lactococcal bacteriocin whose activity depends on the
RT complementary action of two peptides.";
RL J. Bacteriol. 174:5686-5692(1992).
CC -!- FUNCTION: Kills Lactococci.
CC -!- SUBUNIT: Bacteriocin activity requires interaction of alpha and beta
CC peptides in a molar ratio of 7:1 or 8:1 respectively.
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DR PIR; C44918; C44918.
DR PDB; 2JPK; NMR; -; A=1-35.
DR PDB; 2JPM; NMR; -; A=1-35.
DR PDBsum; 2JPK; -.
DR PDBsum; 2JPM; -.
DR AlphaFoldDB; P36962; -.
DR BMRB; P36962; -.
DR SMR; P36962; -.
DR TCDB; 1.C.25.1.1; the lactococcin g (lactococcin g) family.
DR EvolutionaryTrace; P36962; -.
DR GO; GO:0019835; P:cytolysis; IEA:UniProtKB-KW.
DR GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR InterPro; IPR021089; Bacteriocin_lactococcin-G.
DR Pfam; PF11632; LcnG-beta; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Antibiotic; Antimicrobial; Bacteriocin;
KW Direct protein sequencing.
FT PEPTIDE 1..35
FT /note="Bacteriocin lactococcin-G subunit beta"
FT /id="PRO_0000044641"
FT HELIX 5..19
FT /evidence="ECO:0007829|PDB:2JPK"
FT TURN 20..22
FT /evidence="ECO:0007829|PDB:2JPK"
FT TURN 24..26
FT /evidence="ECO:0007829|PDB:2JPK"
FT HELIX 32..34
FT /evidence="ECO:0007829|PDB:2JPK"
SQ SEQUENCE 35 AA; 4110 MW; 76109F8BB0C489D2 CRC64;
KKWGWLAWVD PAYEFIKGFG KGAIKEGNKD KWKNI