ID   LCIA_LACLC              Reviewed;          98 AA.
AC   P0A3M8; Q00561;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 24.
DE   RecName: Full=Lactococcin-A immunity protein;
GN   Name=lciA;
OS   Lactococcus lactis subsp. cremoris (Streptococcus cremoris).
OG   Plasmid p9B4-6.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=1359;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=9B4; PLASMID=p9B4-6;
RX   PubMed=1901707; DOI=10.1128/aem.57.2.492-498.1991;
RA   van Belkum M.J., Hayema B.J., Jeeninga R.E., Kok J., Venema G.;
RT   "Organization and nucleotide sequences of two lactococcal bacteriocin
RT   operons.";
RL   Appl. Environ. Microbiol. 57:492-498(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LMG 2130;
RX   PubMed=1904860; DOI=10.1128/jb.173.12.3879-3887.1991;
RA   Holo H., Nilssen O., Nes I.F.;
RT   "Lactococcin A, a new bacteriocin from Lactococcus lactis subsp. cremoris:
RT   isolation and characterization of the protein and its gene.";
RL   J. Bacteriol. 173:3879-3887(1991).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 75-98.
RC   STRAIN=9B4; PLASMID=p9B4-6;
RX   PubMed=1610182; DOI=10.1128/aem.58.2.572-577.1992;
RA   van Belkum M.J., Kok J., Venema G.;
RT   "Cloning, sequencing, and expression in Escherichia coli of lcnB, a third
RT   bacteriocin determinant from the lactococcal bacteriocin plasmid p9B4-6.";
RL   Appl. Environ. Microbiol. 58:572-577(1992).
CC   -!- FUNCTION: Imparts immunity to lactococcin-A to naturally sensitive host
CC       strains.
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DR   EMBL; S38128; AAB22371.1; -; Genomic_DNA.
DR   EMBL; M63675; AAA25164.1; -; Genomic_DNA.
DR   PIR; B39443; B39443.
DR   PIR; E43943; E43943.
DR   RefSeq; WP_015081787.1; NZ_WJUW01000098.1.
DR   AlphaFoldDB; P0A3M8; -.
DR   SMR; P0A3M8; -.
DR   GO; GO:0030153; P:bacteriocin immunity; IEA:UniProtKB-KW.
DR   InterPro; IPR015046; LciA_Immunity-like.
DR   Pfam; PF08951; EntA_Immun; 1.
PE   4: Predicted;
KW   Bacteriocin immunity; Plasmid.
FT   CHAIN           1..98
FT                   /note="Lactococcin-A immunity protein"
FT                   /id="PRO_0000206198"
SQ   SEQUENCE   98 AA;  11164 MW;  587FE4DB9ED136E7 CRC64;
     MKKKQIEFEN ELRSMLATAL EKDISQEERN ALNIAEKALD NSEYLPKIIL NLRKALTPLA
     INRTLNHDLS ELYKFITSSK ASNKNLGGGL IMSWGRLF