LCL2_AJECH
ID LCL2_AJECH Reviewed; 122 AA.
AC C6HEL8;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-SEP-2009, sequence version 1.
DT 25-MAY-2022, entry version 25.
DE RecName: Full=Long chronological lifespan protein 2;
DE Flags: Precursor;
GN Name=LCL2; ORFNames=HCDG_04885;
OS Ajellomyces capsulatus (strain H143) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=544712;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H143;
RA Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B.,
RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A.M.,
RA Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heiman D.I., Hepburn T.A., Howarth C., Jen D.,
RA Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T.D., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Klein B., McEwen J.G., Puccia R., Goldman G.H., Felipe M.S.,
RA Nino-Vega G., San-Blas G., Taylor J.W., Mendoza L., Galagan J.E.,
RA Nusbaum C., Birren B.W.;
RT "The genome sequence of Ajellomyces capsulatus strain H143.";
RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC degradation (ERAD) pathway. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR EMBL; GG692424; EER41239.1; -; Genomic_DNA.
DR AlphaFoldDB; C6HEL8; -.
DR STRING; 5037.XP_001543563.1; -.
DR EnsemblFungi; EER41239; EER41239; HCDG_04885.
DR VEuPathDB; FungiDB:HCDG_04885; -.
DR eggNOG; ENOG502S416; Eukaryota.
DR HOGENOM; CLU_142363_0_0_1; -.
DR OMA; AQCSHYL; -.
DR Proteomes; UP000002624; Unassembled WGS sequence.
DR InterPro; IPR034543; LCL2.
DR PANTHER; PTHR38425; PTHR38425; 1.
PE 3: Inferred from homology;
KW Reference proteome; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..122
FT /note="Long chronological lifespan protein 2"
FT /id="PRO_0000408584"
SQ SEQUENCE 122 AA; 13434 MW; EF2B1EBE0C642A32 CRC64;
MVHIFTGILL GLLLLATGTQ AQFQFFEQMF GGGQQQQHDS REQNVPSDSD WYQRTYDNAR
CSNYLCPGTL ACVAVPHHCP CQHPAVEDKF ELGDGSAICV SKGGFKFGEA ARKVELARKG
LL