LCL2_AJECN
ID LCL2_AJECN Reviewed; 122 AA.
AC A6QTA3;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 25-MAY-2022, entry version 33.
DE RecName: Full=Long chronological lifespan protein 2;
DE Flags: Precursor;
GN Name=LCL2; ORFNames=HCAG_00609;
OS Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus)
OS (Histoplasma capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma;
OC unclassified Histoplasma.
OX NCBI_TaxID=2059318;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NAm1 / WU24;
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
CC -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC degradation (ERAD) pathway. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR EMBL; CH476655; EDN02745.1; -; Genomic_DNA.
DR RefSeq; XP_001543563.1; XM_001543513.1.
DR AlphaFoldDB; A6QTA3; -.
DR EnsemblFungi; EDN02745; EDN02745; HCAG_00609.
DR GeneID; 5449659; -.
DR KEGG; aje:HCAG_00609; -.
DR VEuPathDB; FungiDB:HCAG_00609; -.
DR HOGENOM; CLU_142363_0_0_1; -.
DR OMA; AQCSHYL; -.
DR OrthoDB; 1618788at2759; -.
DR Proteomes; UP000009297; Unassembled WGS sequence.
DR InterPro; IPR034543; LCL2.
DR PANTHER; PTHR38425; PTHR38425; 1.
PE 3: Inferred from homology;
KW Reference proteome; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..122
FT /note="Long chronological lifespan protein 2"
FT /id="PRO_0000408585"
SQ SEQUENCE 122 AA; 13555 MW; D19FFF9DC357EA4C CRC64;
MVRIFTSILL GLLLLVTGTR SQFQFFEQMF GGGQQQQHDS REQNVPSDSD WYQRTYDNAR
CSNYLCPGTL ACVAVPHHCP CQHPAVEDKF ELGDGSAICV SKGGFKFGEA ARKVELARKG
LL