LCL2_AJEDR
ID LCL2_AJEDR Reviewed; 121 AA.
AC C5GHR3;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 27.
DE RecName: Full=Long chronological lifespan protein 2;
DE Flags: Precursor;
GN Name=LCL2; ORFNames=BDCG_04299;
OS Ajellomyces dermatitidis (strain ER-3 / ATCC MYA-2586) (Blastomyces
OS dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=559297;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ER-3 / ATCC MYA-2586;
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC degradation (ERAD) pathway. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR EMBL; EQ999976; EEQ89179.1; -; Genomic_DNA.
DR AlphaFoldDB; C5GHR3; -.
DR SMR; C5GHR3; -.
DR STRING; 5039.XP_002628368.1; -.
DR EnsemblFungi; EEQ89179; EEQ89179; BDCG_04299.
DR VEuPathDB; FungiDB:BDCG_04299; -.
DR eggNOG; ENOG502S416; Eukaryota.
DR HOGENOM; CLU_142363_0_0_1; -.
DR OMA; AQCSHYL; -.
DR Proteomes; UP000002039; Unassembled WGS sequence.
DR InterPro; IPR034543; LCL2.
DR PANTHER; PTHR38425; PTHR38425; 1.
PE 3: Inferred from homology;
KW Reference proteome; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..121
FT /note="Long chronological lifespan protein 2"
FT /id="PRO_0000408586"
SQ SEQUENCE 121 AA; 13217 MW; 84890942282A0B3D CRC64;
MIHIITGTLL GLLFLATGAR AQFQFFEQMF GGGQQQQESQ EHNVPSDSSW YQRTYDNARC
SDYLCPGTLA CVSVPHHCPC QHPGVEDKFE LGDGSAICVS KGGFKPGEAA RKVELARKGL
L