LCL2_ASPCL
ID LCL2_ASPCL Reviewed; 121 AA.
AC A1C4T4;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 43.
DE RecName: Full=Long chronological lifespan protein 2;
DE Flags: Precursor;
GN Name=lcl2; ORFNames=ACLA_001130;
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1;
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC degradation (ERAD) pathway. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR EMBL; DS027004; EAW14702.1; -; Genomic_DNA.
DR RefSeq; XP_001276128.1; XM_001276127.1.
DR AlphaFoldDB; A1C4T4; -.
DR STRING; 5057.CADACLAP00000164; -.
DR EnsemblFungi; EAW14702; EAW14702; ACLA_001130.
DR GeneID; 4708591; -.
DR KEGG; act:ACLA_001130; -.
DR VEuPathDB; FungiDB:ACLA_001130; -.
DR eggNOG; ENOG502S416; Eukaryota.
DR HOGENOM; CLU_142363_0_0_1; -.
DR OMA; AQCSHYL; -.
DR OrthoDB; 1618788at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR InterPro; IPR034543; LCL2.
DR PANTHER; PTHR38425; PTHR38425; 1.
PE 3: Inferred from homology;
KW Reference proteome; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..121
FT /note="Long chronological lifespan protein 2"
FT /id="PRO_0000408591"
SQ SEQUENCE 121 AA; 13288 MW; 72AE370F0DB0A300 CRC64;
MISVWIRVLG ALLLASVAQA QFQFFEQMFG GGHQEHHQQG SQNSASDSSR YQQLWEATNC
NKYLCPGTLA CVDFPHHCPC EHPNVEDKVE LGEGSAVCIS KGGYKPGEAA RKIELARKGL
L