ID   LCL2_ASPNC              Reviewed;         125 AA.
AC   A2QUM3;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2007, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Long chronological lifespan protein 2;
DE   Flags: Precursor;
GN   Name=lcl2; ORFNames=An09g06130;
OS   Aspergillus niger (strain CBS 513.88 / FGSC A1513).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=425011;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892;
RX   PubMed=17259976; DOI=10.1038/nbt1282;
RA   Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA   Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA   Bendtsen J.D., Benen J.A.E., van den Berg M., Breestraat S., Caddick M.X.,
RA   Contreras R., Cornell M., Coutinho P.M., Danchin E.G.J., Debets A.J.M.,
RA   Dekker P., van Dijck P.W.M., van Dijk A., Dijkhuizen L., Driessen A.J.M.,
RA   d'Enfert C., Geysens S., Goosen C., Groot G.S.P., de Groot P.W.J.,
RA   Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.T.W.,
RA   van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., van der Kaaij R.M.,
RA   Klis F.M., Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA   van der Maarel M.J.E.C., Meulenberg R., Menke H., Mortimer M.A.,
RA   Nielsen J., Oliver S.G., Olsthoorn M., Pal K., van Peij N.N.M.E.,
RA   Ram A.F.J., Rinas U., Roubos J.A., Sagt C.M.J., Schmoll M., Sun J.,
RA   Ussery D., Varga J., Vervecken W., van de Vondervoort P.J.J., Wedler H.,
RA   Woesten H.A.B., Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.;
RT   "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT   niger CBS 513.88.";
RL   Nat. Biotechnol. 25:221-231(2007).
CC   -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC       degradation (ERAD) pathway. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR   EMBL; AM270209; CAL00343.1; -; Genomic_DNA.
DR   RefSeq; XP_001393925.1; XM_001393888.1.
DR   AlphaFoldDB; A2QUM3; -.
DR   PaxDb; A2QUM3; -.
DR   EnsemblFungi; CAL00343; CAL00343; An09g06130.
DR   GeneID; 4984147; -.
DR   KEGG; ang:ANI_1_788084; -.
DR   VEuPathDB; FungiDB:An09g06130; -.
DR   HOGENOM; CLU_142363_0_0_1; -.
DR   Proteomes; UP000006706; Chromosome 1L.
DR   InterPro; IPR034543; LCL2.
DR   PANTHER; PTHR38425; PTHR38425; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..125
FT                   /note="Long chronological lifespan protein 2"
FT                   /id="PRO_5000220482"
FT   REGION          35..54
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        40..54
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   125 AA;  13492 MW;  23B03E962B7AA5BA CRC64;
     MFSWIRLLGA LLLLASVAHA QFQFFEHMFG GGGGGGGHQG RQQAAQNVPS DSSRYQSQWD
     SAHCDKYLCP GTLACVHFPH HCPCPHPDVE EKVELGEGSA VCVSKGGYKE GEAARKIELA
     RKGLL