LCL2_BLAGS
ID LCL2_BLAGS Reviewed; 121 AA.
AC C5JF45; A0A179UBW4;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 28.
DE RecName: Full=Long chronological lifespan protein 2;
DE Flags: Precursor;
GN Name=LCL2; ORFNames=BDBG_01276;
OS Blastomyces gilchristii (strain SLH14081) (Blastomyces dermatitidis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Blastomyces.
OX NCBI_TaxID=559298;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SLH14081;
RX PubMed=26439490; DOI=10.1371/journal.pgen.1005493;
RA Munoz J.F., Gauthier G.M., Desjardins C.A., Gallo J.E., Holder J.,
RA Sullivan T.D., Marty A.J., Carmen J.C., Chen Z., Ding L., Gujja S.,
RA Magrini V., Misas E., Mitreva M., Priest M., Saif S., Whiston E.A.,
RA Young S., Zeng Q., Goldman W.E., Mardis E.R., Taylor J.W., McEwen J.G.,
RA Clay O.K., Klein B.S., Cuomo C.A.;
RT "The dynamic genome and transcriptome of the human fungal pathogen
RT Blastomyces and close relative Emmonsia.";
RL PLoS Genet. 11:E1005493-E1005493(2015).
CC -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC degradation (ERAD) pathway. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=OAT04779.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; GG657449; OAT04779.1; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_002628368.1; XM_002628322.1.
DR AlphaFoldDB; C5JF45; -.
DR SMR; C5JF45; -.
DR EnsemblFungi; OAT04779; OAT04779; BDBG_01276.
DR HOGENOM; CLU_142363_0_0_1; -.
DR Proteomes; UP000002038; Unassembled WGS sequence.
DR InterPro; IPR034543; LCL2.
DR PANTHER; PTHR38425; PTHR38425; 1.
PE 3: Inferred from homology;
KW Reference proteome; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..121
FT /note="Long chronological lifespan protein 2"
FT /id="PRO_0000408587"
SQ SEQUENCE 121 AA; 13217 MW; 84890942282A0B3D CRC64;
MIHIITGTLL GLLFLATGAR AQFQFFEQMF GGGQQQQESQ EHNVPSDSSW YQRTYDNARC
SDYLCPGTLA CVSVPHHCPC QHPGVEDKFE LGDGSAICVS KGGFKPGEAA RKVELARKGL
L