LCL2_CANGA
ID LCL2_CANGA Reviewed; 119 AA.
AC Q6FIV0;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=Long chronological lifespan protein 2;
DE Flags: Precursor;
GN Name=LCL2; OrderedLocusNames=CAGL0M11572g;
OS Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS Y-65) (Yeast) (Torulopsis glabrata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC Nakaseomyces/Candida clade.
OX NCBI_TaxID=284593;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC degradation (ERAD) pathway. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR EMBL; CR380959; CAG62824.1; -; Genomic_DNA.
DR RefSeq; XP_449844.1; XM_449844.1.
DR AlphaFoldDB; Q6FIV0; -.
DR STRING; 5478.XP_449844.1; -.
DR EnsemblFungi; CAG62824; CAG62824; CAGL0M11572g.
DR GeneID; 2891238; -.
DR KEGG; cgr:CAGL0M11572g; -.
DR CGD; CAL0137141; CAGL0M11572g.
DR VEuPathDB; FungiDB:CAGL0M11572g; -.
DR eggNOG; ENOG502S416; Eukaryota.
DR HOGENOM; CLU_142363_1_0_1; -.
DR InParanoid; Q6FIV0; -.
DR OMA; KPATHDE; -.
DR Proteomes; UP000002428; Chromosome M.
DR InterPro; IPR034543; LCL2.
DR PANTHER; PTHR38425; PTHR38425; 1.
PE 3: Inferred from homology;
KW Reference proteome; Signal.
FT SIGNAL 1..14
FT /evidence="ECO:0000255"
FT CHAIN 15..119
FT /note="Long chronological lifespan protein 2"
FT /id="PRO_0000408601"
SQ SEQUENCE 119 AA; 13477 MW; 98A24AC112C3B154 CRC64;
MNLLMVLFVA QAHAFFFGQQ QQQQQQQASY EDRVLDSGCA KYLCSDTLEC VDSWKDCPCP
FPKSQLKCML PKGSNRPYVC ISKPATHDEK LNLIYDDPVQ GPKAAIKGMR DCGWVQQNL