LCL2_DEBHA
ID LCL2_DEBHA Reviewed; 131 AA.
AC Q6BNN2;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 25-MAY-2022, entry version 62.
DE RecName: Full=Long chronological lifespan protein 2;
DE Flags: Precursor;
GN Name=LCL2; OrderedLocusNames=DEHA2E20372g;
OS Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX NCBI_TaxID=284592;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC degradation (ERAD) pathway. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR EMBL; CR382137; CAG88461.1; -; Genomic_DNA.
DR RefSeq; XP_460188.1; XM_460188.1.
DR AlphaFoldDB; Q6BNN2; -.
DR SMR; Q6BNN2; -.
DR STRING; 4959.XP_460188.1; -.
DR EnsemblFungi; CAG88461; CAG88461; DEHA2E20372g.
DR GeneID; 2902762; -.
DR KEGG; dha:DEHA2E20372g; -.
DR VEuPathDB; FungiDB:DEHA2E20372g; -.
DR eggNOG; ENOG502S416; Eukaryota.
DR HOGENOM; CLU_142363_1_0_1; -.
DR InParanoid; Q6BNN2; -.
DR OMA; KPATHDE; -.
DR OrthoDB; 1618788at2759; -.
DR Proteomes; UP000000599; Chromosome E.
DR InterPro; IPR034543; LCL2.
DR PANTHER; PTHR38425; PTHR38425; 1.
PE 3: Inferred from homology;
KW Reference proteome; Signal.
FT SIGNAL 1..17
FT /evidence="ECO:0000255"
FT CHAIN 18..131
FT /note="Long chronological lifespan protein 2"
FT /id="PRO_0000408607"
SQ SEQUENCE 131 AA; 14681 MW; 3BEBB09E60FB5DB9 CRC64;
MIGNIAYILF TLTVVSANLF DFIQNQFQGN NQQAQRQTPG EYENANLNSG CSKYLCPDTS
ICVDEPKFCP CPYPSSQLRC FLPNGRYVCI SKPAGEVSLN YADPKTNWKI DAKDDNIRDC
GWVGRAWKGL V