LCL2_KOMPG
ID LCL2_KOMPG Reviewed; 120 AA.
AC C4R2P5;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 07-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 47.
DE RecName: Full=Long chronological lifespan protein 2;
DE Flags: Precursor;
GN Name=LCL2; OrderedLocusNames=PAS_chr2-2_0158;
OS Komagataella phaffii (strain GS115 / ATCC 20864) (Yeast) (Pichia pastoris).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Phaffomycetaceae; Komagataella.
OX NCBI_TaxID=644223;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GS115 / ATCC 20864;
RX PubMed=19465926; DOI=10.1038/nbt.1544;
RA De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S.,
RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.;
RT "Genome sequence of the recombinant protein production host Pichia
RT pastoris.";
RL Nat. Biotechnol. 27:561-566(2009).
CC -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC degradation (ERAD) pathway. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR EMBL; FN392320; CAY69769.1; -; Genomic_DNA.
DR RefSeq; XP_002492049.1; XM_002492004.1.
DR AlphaFoldDB; C4R2P5; -.
DR STRING; 644223.C4R2P5; -.
DR EnsemblFungi; CAY69769; CAY69769; PAS_chr2-2_0158.
DR GeneID; 8198268; -.
DR KEGG; ppa:PAS_chr2-2_0158; -.
DR eggNOG; ENOG502S416; Eukaryota.
DR HOGENOM; CLU_142363_1_0_1; -.
DR InParanoid; C4R2P5; -.
DR OMA; AQCSHYL; -.
DR Proteomes; UP000000314; Chromosome 2.
DR InterPro; IPR034543; LCL2.
DR PANTHER; PTHR38425; PTHR38425; 1.
PE 3: Inferred from homology;
KW Reference proteome; Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..120
FT /note="Long chronological lifespan protein 2"
FT /id="PRO_0000408622"
SQ SEQUENCE 120 AA; 13599 MW; 2195AA7A7A714FCD CRC64;
MRGFVVATII VGAANCVMAF DFEQFFGGQN RQQQRTQQNN QPQDYEQQQL NSDCQKYLCP
ETFACVAKPV DCPCPFPQSQ IKCVFPDKQN FVCISSPVDN VNGVPVRDCK WVEKAWKGLL