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LCL2_LACTC
ID   LCL2_LACTC              Reviewed;         127 AA.
AC   C5DMZ6;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Long chronological lifespan protein 2;
DE   Flags: Precursor;
GN   Name=LCL2; OrderedLocusNames=KLTH0G12958g;
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC       degradation (ERAD) pathway. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR   EMBL; CU928171; CAR25157.1; -; Genomic_DNA.
DR   RefSeq; XP_002555594.1; XM_002555548.1.
DR   AlphaFoldDB; C5DMZ6; -.
DR   STRING; 559295.C5DMZ6; -.
DR   EnsemblFungi; CAR25157; CAR25157; KLTH0G12958g.
DR   GeneID; 8293877; -.
DR   KEGG; lth:KLTH0G12958g; -.
DR   eggNOG; ENOG502S416; Eukaryota.
DR   HOGENOM; CLU_142363_1_0_1; -.
DR   InParanoid; C5DMZ6; -.
DR   OMA; KPATHDE; -.
DR   OrthoDB; 1618788at2759; -.
DR   Proteomes; UP000002036; Chromosome G.
DR   InterPro; IPR034543; LCL2.
DR   PANTHER; PTHR38425; PTHR38425; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..127
FT                   /note="Long chronological lifespan protein 2"
FT                   /id="PRO_0000408609"
SQ   SEQUENCE   127 AA;  14178 MW;  9656FCF8F800D5DA CRC64;
     MRGSSLGLYF ILPIASGFFF DFNQRNQHEG QQPQVSYEDK VLNNDCADFL CPDTLTCVKT
     AKDCPCPFPK SQLRCTLPNG QFVCISKPAT HDKNLNAIYD DPVKGPQSKI KGLRDCGWVQ
     DAYKGIV
 
 
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