ID   LCL2_LODEL              Reviewed;         144 AA.
AC   A5E0N1;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=Long chronological lifespan protein 2;
DE   Flags: Precursor;
GN   Name=LCL2; ORFNames=LELG_03168;
OS   Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC
OS   1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade;
OC   Lodderomyces.
OX   NCBI_TaxID=379508;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11503 / BCRC 21390 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL
RC   YB-4239;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC       degradation (ERAD) pathway. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR   EMBL; CH981527; EDK44989.1; -; Genomic_DNA.
DR   RefSeq; XP_001525240.1; XM_001525190.1.
DR   AlphaFoldDB; A5E0N1; -.
DR   SMR; A5E0N1; -.
DR   STRING; 379508.A5E0N1; -.
DR   EnsemblFungi; EDK44989; EDK44989; LELG_03168.
DR   GeneID; 5232504; -.
DR   KEGG; lel:LELG_03168; -.
DR   VEuPathDB; FungiDB:LELG_03168; -.
DR   eggNOG; ENOG502S416; Eukaryota.
DR   HOGENOM; CLU_142363_1_0_1; -.
DR   InParanoid; A5E0N1; -.
DR   OMA; AQCSHYL; -.
DR   OrthoDB; 1618788at2759; -.
DR   Proteomes; UP000001996; Unassembled WGS sequence.
DR   InterPro; IPR034543; LCL2.
DR   PANTHER; PTHR38425; PTHR38425; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..144
FT                   /note="Long chronological lifespan protein 2"
FT                   /id="PRO_0000408611"
SQ   SEQUENCE   144 AA;  15945 MW;  EBDB42096AB2C26C CRC64;
     MLQKFLICLS LIFTLASANL FDFLNNQFQG GNGGGGGGRH QNGGSKSPQQ HEEAMLNANC
     NTYLCPDTGI CVDAPKFCPC PYPSSQLRCF LPDGRYVCIS KPAGYGIADK YNDPQTNFKI
     DAKDDNIRDC GWVNRAWRNE KLKK