ID   LCL2_NEOFI              Reviewed;         122 AA.
AC   A1CZR3;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Long chronological lifespan protein 2;
DE   Flags: Precursor;
GN   Name=lcl2; ORFNames=NFIA_038070;
OS   Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS   / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=331117;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181
RC   / WB 181;
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC       degradation (ERAD) pathway. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR   EMBL; DS027686; EAW24233.1; -; Genomic_DNA.
DR   RefSeq; XP_001266130.1; XM_001266129.1.
DR   AlphaFoldDB; A1CZR3; -.
DR   SMR; A1CZR3; -.
DR   STRING; 36630.CADNFIAP00003259; -.
DR   EnsemblFungi; EAW24233; EAW24233; NFIA_038070.
DR   GeneID; 4592748; -.
DR   KEGG; nfi:NFIA_038070; -.
DR   VEuPathDB; FungiDB:NFIA_038070; -.
DR   eggNOG; ENOG502S416; Eukaryota.
DR   HOGENOM; CLU_142363_0_0_1; -.
DR   OMA; AQCSHYL; -.
DR   OrthoDB; 1618788at2759; -.
DR   Proteomes; UP000006702; Unassembled WGS sequence.
DR   InterPro; IPR034543; LCL2.
DR   PANTHER; PTHR38425; PTHR38425; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..122
FT                   /note="Long chronological lifespan protein 2"
FT                   /id="PRO_0000408614"
SQ   SEQUENCE   122 AA;  13344 MW;  BCBC4937B29F38FB CRC64;
     MLSSWVRCLG ALLLLASVAQ AQFQFFEHMF GGGHQEHHQQ NTQNSASDSA RYQQLWEGTN
     CNKYLCPGTL ACVDFPHHCP CAHPSVEDKV ELGEGSAVCI SKGGYKPGEA ARKIELARKG
     LL