ID   LCL2_PARBA              Reviewed;         123 AA.
AC   C1H0A6;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   26-MAY-2009, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Long chronological lifespan protein 2;
DE   Flags: Precursor;
GN   Name=LCL2; ORFNames=PAAG_04200;
OS   Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides
OS   brasiliensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX   NCBI_TaxID=502779;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-826 / Pb01;
RX   PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA   Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA   Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA   Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA   Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA   Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA   Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA   Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA   Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT   "Comparative genomic analysis of human fungal pathogens causing
RT   paracoccidioidomycosis.";
RL   PLoS Genet. 7:E1002345-E1002345(2011).
CC   -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC       degradation (ERAD) pathway. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EEH33147.2; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; KN294001; EEH33147.2; ALT_INIT; Genomic_DNA.
DR   RefSeq; XP_002793928.2; XM_002793882.2.
DR   AlphaFoldDB; C1H0A6; -.
DR   STRING; 1048829.XP_002793928.1; -.
DR   EnsemblFungi; EEH33147; EEH33147; PAAG_04200.
DR   GeneID; 9097010; -.
DR   KEGG; pbl:PAAG_04200; -.
DR   eggNOG; ENOG502S416; Eukaryota.
DR   HOGENOM; CLU_142363_0_0_1; -.
DR   OrthoDB; 1618788at2759; -.
DR   Proteomes; UP000002059; Partially assembled WGS sequence.
DR   InterPro; IPR034543; LCL2.
DR   PANTHER; PTHR38425; PTHR38425; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..123
FT                   /note="Long chronological lifespan protein 2"
FT                   /id="PRO_0000408616"
SQ   SEQUENCE   123 AA;  13583 MW;  44231B2AC648B498 CRC64;
     MFHILIGALL GLLFLATGTR AQFQFFEQMF GGGGHQQQQD HREQNVASDS SWYQRNYDNA
     HCSDYLCPGT LACVSVPHHC PCQHPDVEDK FELGDGSAIC ISKGGFKANE AARKVELARK
     GLL