LCL2_PARBD
ID LCL2_PARBD Reviewed; 123 AA.
AC C1GJL9;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 26-MAY-2009, sequence version 1.
DT 25-MAY-2022, entry version 32.
DE RecName: Full=Long chronological lifespan protein 2;
DE Flags: Precursor;
GN Name=LCL2; ORFNames=PADG_07455;
OS Paracoccidioides brasiliensis (strain Pb18).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Paracoccidioides.
OX NCBI_TaxID=502780;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pb18;
RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345;
RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., Goldberg J.,
RA Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., Grynberg M.,
RA Gujja S., Heiman D.I., Henn M.R., Kodira C.D., Leon-Narvaez H.,
RA Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., Morais F.V., Pereira M.,
RA Rodriguez-Brito S., Sakthikumar S., Salem-Izacc S.M., Sykes S.M.,
RA Teixeira M.M., Vallejo M.C., Walter M.E., Yandava C., Young S., Zeng Q.,
RA Zucker J., Felipe M.S., Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G.,
RA Puccia R., San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.;
RT "Comparative genomic analysis of human fungal pathogens causing
RT paracoccidioidomycosis.";
RL PLoS Genet. 7:E1002345-E1002345(2011).
CC -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC degradation (ERAD) pathway. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EEH42635.2; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; KN275967; EEH42635.2; ALT_INIT; Genomic_DNA.
DR RefSeq; XP_010762743.1; XM_010764441.1.
DR AlphaFoldDB; C1GJL9; -.
DR STRING; 121759.XP_010762743.1; -.
DR EnsemblFungi; EEH42635; EEH42635; PADG_07455.
DR GeneID; 22585944; -.
DR KEGG; pbn:PADG_07455; -.
DR eggNOG; ENOG502S416; Eukaryota.
DR HOGENOM; CLU_142363_0_0_1; -.
DR Proteomes; UP000001628; Unassembled WGS sequence.
DR InterPro; IPR034543; LCL2.
DR PANTHER; PTHR38425; PTHR38425; 1.
PE 3: Inferred from homology;
KW Reference proteome; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..123
FT /note="Long chronological lifespan protein 2"
FT /id="PRO_0000408617"
SQ SEQUENCE 123 AA; 13655 MW; 7CC1BB0264C29C38 CRC64;
MFHILIGALL GLLFLATETR AQFQFFEQMF GGGGHQQQQD HREQNVASDS SWYQRNYDNA
HCSDYLCPGT LACVSVPHHC PCQHPDVEDK FELGDGSAIC ISKGGFKANE AARKVELARK
GLL