ID   LCL2_PENRW              Reviewed;         122 AA.
AC   B6HU36;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 1.
DT   03-AUG-2022, entry version 42.
DE   RecName: Full=Long chronological lifespan protein 2;
DE   Flags: Precursor;
GN   Name=lcl2; ORFNames=Pc22g14060;
OS   Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin
OS   54-1255) (Penicillium chrysogenum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium;
OC   Penicillium chrysogenum species complex.
OX   NCBI_TaxID=500485;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255;
RX   PubMed=18820685; DOI=10.1038/nbt.1498;
RA   van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M.,
RA   Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M.,
RA   Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F.,
RA   Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., van der Klei I.J.,
RA   van Peij N.N.M.E., Veenhuis M., von Doehren H., Wagner C., Wortman J.R.,
RA   Bovenberg R.A.L.;
RT   "Genome sequencing and analysis of the filamentous fungus Penicillium
RT   chrysogenum.";
RL   Nat. Biotechnol. 26:1161-1168(2008).
CC   -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC       degradation (ERAD) pathway. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR   EMBL; AM920437; CAP98694.1; -; Genomic_DNA.
DR   RefSeq; XP_002565330.1; XM_002565284.1.
DR   AlphaFoldDB; B6HU36; -.
DR   STRING; 1108849.XP_002565330.1; -.
DR   EnsemblFungi; CAP98694; CAP98694; PCH_Pc22g14060.
DR   GeneID; 8311317; -.
DR   KEGG; pcs:Pc22g14060; -.
DR   VEuPathDB; FungiDB:PCH_Pc22g14060; -.
DR   eggNOG; ENOG502S416; Eukaryota.
DR   HOGENOM; CLU_142363_0_0_1; -.
DR   OMA; AQCSHYL; -.
DR   OrthoDB; 1618788at2759; -.
DR   BioCyc; PCHR:PC22G14060-MON; -.
DR   Proteomes; UP000000724; Contig Pc00c22.
DR   InterPro; IPR034543; LCL2.
DR   PANTHER; PTHR38425; PTHR38425; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..122
FT                   /note="Long chronological lifespan protein 2"
FT                   /id="PRO_5000410280"
SQ   SEQUENCE   122 AA;  13632 MW;  78DBA9DE2C76BE9B CRC64;
     MLQSWRQALW ALLLLVSVAQ AQFNFFDQMF GGGEQQRQQQ RSQNSPSDSD RYQQMWNGAQ
     CDHYLCPGTL ACVHFPHHCP CPHPDVEEKV ELGEGSAVCV SKGGFKAGEA ARKIELARKG
     LL