LCL2_PICST
ID LCL2_PICST Reviewed; 133 AA.
AC A3LY18;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 03-APR-2007, sequence version 1.
DT 25-MAY-2022, entry version 50.
DE RecName: Full=Long chronological lifespan protein 2;
DE Flags: Precursor;
GN Name=LCL2; ORFNames=PICST_48963;
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC degradation (ERAD) pathway. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR EMBL; CP000500; ABN67558.1; -; Genomic_DNA.
DR RefSeq; XP_001385587.1; XM_001385550.1.
DR AlphaFoldDB; A3LY18; -.
DR STRING; 4924.XP_001385587.1; -.
DR EnsemblFungi; ABN67558; ABN67558; PICST_48963.
DR GeneID; 4839859; -.
DR KEGG; pic:PICST_48963; -.
DR eggNOG; ENOG502S416; Eukaryota.
DR HOGENOM; CLU_142363_1_0_1; -.
DR InParanoid; A3LY18; -.
DR OMA; KPATHDE; -.
DR OrthoDB; 1618788at2759; -.
DR Proteomes; UP000002258; Chromosome 6.
DR InterPro; IPR034543; LCL2.
DR PANTHER; PTHR38425; PTHR38425; 1.
PE 3: Inferred from homology;
KW Reference proteome; Signal.
FT SIGNAL 1..17
FT /evidence="ECO:0000255"
FT CHAIN 18..133
FT /note="Long chronological lifespan protein 2"
FT /id="PRO_0000408623"
SQ SEQUENCE 133 AA; 14837 MW; 1892D8978C310959 CRC64;
MIRVISLFLV FVSLASANIF DFLNNNFAGR GQQQGGQVQT PEQYENAILN TNCGKYVCPD
TGMCVEAPKF CPCPYPSSQL RCFLPDGRYL CISKPAGDIS AKYDDPKSNW KVDAKDDNIR
DCGWVSRAWR GLV