LCL2_PODAN
ID LCL2_PODAN Reviewed; 132 AA.
AC B2ABT3; A0A090CBC0;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 20-MAY-2008, sequence version 1.
DT 25-MAY-2022, entry version 37.
DE RecName: Full=Long chronological lifespan protein 2;
DE Flags: Precursor;
GN Name=LCL2; OrderedLocusNames=Pa_0_1040; ORFNames=PODANS_0_1040;
OS Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383)
OS (Pleurage anserina).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Podosporaceae; Podospora;
OC Podospora anserina.
OX NCBI_TaxID=515849;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S / ATCC MYA-4624 / DSM 980 / FGSC 10383;
RX PubMed=18460219; DOI=10.1186/gb-2008-9-5-r77;
RA Espagne E., Lespinet O., Malagnac F., Da Silva C., Jaillon O., Porcel B.M.,
RA Couloux A., Aury J.-M., Segurens B., Poulain J., Anthouard V.,
RA Grossetete S., Khalili H., Coppin E., Dequard-Chablat M., Picard M.,
RA Contamine V., Arnaise S., Bourdais A., Berteaux-Lecellier V., Gautheret D.,
RA de Vries R.P., Battaglia E., Coutinho P.M., Danchin E.G.J., Henrissat B.,
RA El Khoury R., Sainsard-Chanet A., Boivin A., Pinan-Lucarre B., Sellem C.H.,
RA Debuchy R., Wincker P., Weissenbach J., Silar P.;
RT "The genome sequence of the model ascomycete fungus Podospora anserina.";
RL Genome Biol. 9:R77.1-R77.22(2008).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=S / ATCC MYA-4624 / DSM 980 / FGSC 10383;
RX PubMed=24558260; DOI=10.1534/genetics.113.159988;
RA Grognet P., Bidard F., Kuchly C., Tong L.C.H., Coppin E., Benkhali J.A.,
RA Couloux A., Wincker P., Debuchy R., Silar P.;
RT "Maintaining two mating types: Structure of the mating type locus and its
RT role in heterokaryosis in Podospora anserina.";
RL Genetics 197:421-432(2014).
CC -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC degradation (ERAD) pathway. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR EMBL; CU633446; CAP60921.1; -; Genomic_DNA.
DR EMBL; FO904937; CDP24936.1; -; Genomic_DNA.
DR RefSeq; XP_001903149.1; XM_001903114.1.
DR AlphaFoldDB; B2ABT3; -.
DR STRING; 5145.XP_001903149.1; -.
DR EnsemblFungi; CAP60921; CAP60921; PODANS_0_1040.
DR GeneID; 6187218; -.
DR KEGG; pan:PODANSg161; -.
DR VEuPathDB; FungiDB:PODANS_0_1040; -.
DR eggNOG; ENOG502S416; Eukaryota.
DR HOGENOM; CLU_142363_0_0_1; -.
DR OrthoDB; 1618788at2759; -.
DR Proteomes; UP000001197; Chromosome 2.
DR InterPro; IPR034543; LCL2.
DR PANTHER; PTHR38425; PTHR38425; 1.
PE 3: Inferred from homology;
KW Reference proteome; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..132
FT /note="Long chronological lifespan protein 2"
FT /id="PRO_0000408624"
FT REGION 33..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 132 AA; 14354 MW; 322EE7929E147A26 CRC64;
MRSLSLILLA LATMLTPISA QFGFFDQMFG GGGGGEQEQH HGHGHGGHQR QQQNAPSDGA
GYRAQYARLH CDNYLCPDTL ACVHFPHHCP CPWPAHEEKV ELAEGQRICV SHGGFKAGEA
ARKVELARKG LL