LCL2_SORMK
ID LCL2_SORMK Reviewed; 133 AA.
AC D1ZMX7; F7W901;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 09-FEB-2010, sequence version 1.
DT 25-MAY-2022, entry version 31.
DE RecName: Full=Long chronological lifespan protein 2;
DE Flags: Precursor;
GN Name=LCL2; ORFNames=SMAC_07951;
OS Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / K-hell).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Sordaria.
OX NCBI_TaxID=771870;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-333 / DSM 997 / K(L3346) / K-hell;
RX PubMed=20386741; DOI=10.1371/journal.pgen.1000891;
RA Nowrousian M., Stajich J.E., Chu M., Engh I., Espagne E., Halliday K.,
RA Kamerewerd J., Kempken F., Knab B., Kuo H.-C., Osiewacz H.D., Poeggeler S.,
RA Read N.D., Seiler S., Smith K.M., Zickler D., Kueck U., Freitag M.;
RT "De novo assembly of a 40 Mb eukaryotic genome from short sequence reads:
RT Sordaria macrospora, a model organism for fungal morphogenesis.";
RL PLoS Genet. 6:E1000891-E1000891(2010).
CC -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC degradation (ERAD) pathway. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR EMBL; CABT02000048; CCC13882.1; -; Genomic_DNA.
DR RefSeq; XP_003346303.1; XM_003346255.1.
DR AlphaFoldDB; D1ZMX7; -.
DR STRING; 771870.D1ZMX7; -.
DR EnsemblFungi; CCC13882; CCC13882; SMAC_07951.
DR GeneID; 10803687; -.
DR KEGG; smp:SMAC_07951; -.
DR VEuPathDB; FungiDB:SMAC_07951; -.
DR eggNOG; ENOG502S416; Eukaryota.
DR HOGENOM; CLU_142363_0_0_1; -.
DR InParanoid; D1ZMX7; -.
DR OMA; AQCSHYL; -.
DR OrthoDB; 1618788at2759; -.
DR Proteomes; UP000001881; Unassembled WGS sequence.
DR InterPro; IPR034543; LCL2.
DR PANTHER; PTHR38425; PTHR38425; 1.
PE 3: Inferred from homology;
KW Reference proteome; Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..133
FT /note="Long chronological lifespan protein 2"
FT /id="PRO_0000408628"
FT REGION 32..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..60
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 133 AA; 14691 MW; AF04ABDAD9505D68 CRC64;
MRTLTLLLSL LFLASPIAAQ FGSFFDQMFG GGGHGGHGHQ HQQQHQGHGQ QQHPNVPSDP
SIYQANYQRA HCDKYLCPDT LACVHYPHHC PCPWPSHEDK VELAEGQRVC VSRGGFKAGE
AARKIELARQ GLL