ID   LCL2_VANPO              Reviewed;         143 AA.
AC   A7TJ20;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=Long chronological lifespan protein 2;
DE   Flags: Precursor;
GN   Name=LCL2; ORFNames=Kpol_1033p23;
OS   Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS
OS   2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17) (Kluyveromyces polysporus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Vanderwaltozyma.
OX   NCBI_TaxID=436907;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL
RC   Y-8283 / UCD 57-17;
RX   PubMed=17494770; DOI=10.1073/pnas.0608218104;
RA   Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., Wolfe K.H.;
RT   "Independent sorting-out of thousands of duplicated gene pairs in two yeast
RT   species descended from a whole-genome duplication.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007).
CC   -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC       degradation (ERAD) pathway. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR   EMBL; DS480399; EDO17719.1; -; Genomic_DNA.
DR   RefSeq; XP_001645577.1; XM_001645527.1.
DR   AlphaFoldDB; A7TJ20; -.
DR   STRING; 436907.A7TJ20; -.
DR   PRIDE; A7TJ20; -.
DR   EnsemblFungi; EDO17719; EDO17719; Kpol_1033p23.
DR   GeneID; 5545961; -.
DR   KEGG; vpo:Kpol_1033p23; -.
DR   eggNOG; ENOG502S416; Eukaryota.
DR   HOGENOM; CLU_142363_1_0_1; -.
DR   InParanoid; A7TJ20; -.
DR   OMA; AQCSHYL; -.
DR   OrthoDB; 1618788at2759; -.
DR   PhylomeDB; A7TJ20; -.
DR   Proteomes; UP000000267; Unassembled WGS sequence.
DR   InterPro; IPR034543; LCL2.
DR   PANTHER; PTHR38425; PTHR38425; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..143
FT                   /note="Long chronological lifespan protein 2"
FT                   /id="PRO_0000408630"
SQ   SEQUENCE   143 AA;  15983 MW;  DEAC72D68E3A0EB0 CRC64;
     MIAGFFTRFL FAILLLLPYS QGFFNFQGNQ RQQQQQHHQN ANPAEGFLSP HEERALSNQC
     PGYLCPDTEE CVDSPSSCPC PFPGSQLKCS LPDGTFVCIS KPATDNEDIN RKYDDLSGNS
     KIKFNGVRDC GWVYEMAVKG FST