LCL2_YEAS1
ID LCL2_YEAS1 Reviewed; 131 AA.
AC B3LT72;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 1.
DT 25-MAY-2022, entry version 32.
DE RecName: Full=Long chronological lifespan protein 2;
DE Flags: Precursor;
GN Name=LCL2; ORFNames=SCRG_05088;
OS Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=285006;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RM11-1a;
RG The Broad Institute Genome Sequencing Platform;
RA Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Cuomo C.,
RA Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., Young S.K.,
RA LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA O'Leary S., Kodira C.D., Zeng Q., Yandava C., Alvarado L., Pratt S.,
RA Kruglyak L.;
RT "Annotation of the Saccharomyces cerevisiae RM11-1a genome.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC degradation (ERAD) pathway. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR EMBL; CH408054; EDV09407.1; -; Genomic_DNA.
DR AlphaFoldDB; B3LT72; -.
DR EnsemblFungi; EDV09407; EDV09407; SCRG_05088.
DR HOGENOM; CLU_142363_1_0_1; -.
DR Proteomes; UP000008335; Unassembled WGS sequence.
DR InterPro; IPR034543; LCL2.
DR PANTHER; PTHR38425; PTHR38425; 1.
PE 3: Inferred from homology;
KW Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..131
FT /note="Long chronological lifespan protein 2"
FT /id="PRO_0000408633"
SQ SEQUENCE 131 AA; 14922 MW; 1DC418D21CB9B554 CRC64;
MSQSRWSIVL IFALFIFGST GVNAFFNFGH HQQQQQQQQQ SYEDQVLNNP CDGYLCPDTL
TCVAQQKDCP CPFPKSQLKC VLPDNKFVCI SKPATHNEKF RAIYDDPVKG PKAKNKGFRD
CGWVSDAYKN H