LCL2_YEAS8
ID LCL2_YEAS8 Reviewed; 131 AA.
AC C8ZD75;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 03-NOV-2009, sequence version 1.
DT 25-MAY-2022, entry version 30.
DE RecName: Full=Long chronological lifespan protein 2;
DE Flags: Precursor;
GN Name=LCL2; ORFNames=EC1118_1L10_1849g;
OS Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's
OS yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=643680;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lalvin EC1118 / Prise de mousse;
RX PubMed=19805302; DOI=10.1073/pnas.0904673106;
RA Novo M., Bigey F., Beyne E., Galeote V., Gavory F., Mallet S., Cambon B.,
RA Legras J.-L., Wincker P., Casaregola S., Dequin S.;
RT "Eukaryote-to-eukaryote gene transfer events revealed by the genome
RT sequence of the wine yeast Saccharomyces cerevisiae EC1118.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:16333-16338(2009).
CC -!- FUNCTION: Probable component of the endoplasmic reticulum-associated
CC degradation (ERAD) pathway. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the LCL2 family. {ECO:0000305}.
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DR EMBL; FN393078; CAY81341.1; -; Genomic_DNA.
DR AlphaFoldDB; C8ZD75; -.
DR EnsemblFungi; CAY81341; CAY81341; EC1118_1L10_1849g.
DR HOGENOM; CLU_142363_1_0_1; -.
DR Proteomes; UP000000286; Chromosome XII, Scaffold EC1118_1L10.
DR InterPro; IPR034543; LCL2.
DR PANTHER; PTHR38425; PTHR38425; 1.
PE 3: Inferred from homology;
KW Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..131
FT /note="Long chronological lifespan protein 2"
FT /id="PRO_0000408636"
SQ SEQUENCE 131 AA; 14922 MW; 1DC418D21CB9B554 CRC64;
MSQSRWSIVL IFALFIFGST GVNAFFNFGH HQQQQQQQQQ SYEDQVLNNP CDGYLCPDTL
TCVAQQKDCP CPFPKSQLKC VLPDNKFVCI SKPATHNEKF RAIYDDPVKG PKAKNKGFRD
CGWVSDAYKN H