ID   LCN2_LACLL              Reviewed;         922 AA.
AC   P37609;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Lacticin 481/lactococcin biosynthesis protein LcnDR2;
GN   Name=lcnDR2;
OS   Lactococcus lactis subsp. lactis (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=1360;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ADRIA 85LO30;
RX   PubMed=8017945; DOI=10.1128/aem.60.5.1652-1657.1994;
RA   Rince A., Dufour A., le Pogam S., Thuault D., Bourgeois C.M., Pennec J.P.;
RT   "Cloning, expression, and nucleotide sequence of genes involved in
RT   production of lactococcin DR, a bacteriocin from Lactococcus lactis subsp.
RT   lactis.";
RL   Appl. Environ. Microbiol. 60:1652-1657(1994).
CC   -!- FUNCTION: Could be implicated in the processing or the export process
CC       of the lantibiotic lacticin 481/lactococcin DR.
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DR   EMBL; U91581; AAC72258.1; -; Genomic_DNA.
DR   PIR; C47342; C47342.
DR   AlphaFoldDB; P37609; -.
DR   SMR; P37609; -.
DR   PRIDE; P37609; -.
DR   GO; GO:0030152; P:bacteriocin biosynthetic process; IEA:UniProtKB-KW.
DR   CDD; cd04792; LanM-like; 1.
DR   InterPro; IPR007822; LANC-like.
DR   InterPro; IPR025410; Lant_dehyd.
DR   InterPro; IPR017146; Lanti_2_LanM.
DR   Pfam; PF13575; DUF4135; 1.
DR   Pfam; PF05147; LANC_like; 1.
DR   PIRSF; PIRSF037228; Lant_mod_RumM; 1.
DR   PRINTS; PR01950; LANCSUPER.
DR   SMART; SM01260; LANC_like; 1.
DR   TIGRFAMs; TIGR03897; lanti_2_LanM; 1.
PE   4: Predicted;
KW   Antibiotic biosynthesis; Bacteriocin biosynthesis.
FT   CHAIN           1..922
FT                   /note="Lacticin 481/lactococcin biosynthesis protein
FT                   LcnDR2"
FT                   /id="PRO_0000084367"
SQ   SEQUENCE   922 AA;  106709 MW;  440965FAAA67EFA7 CRC64;
     MKKKTYQFEK FLKNTFDQFS IKQNEVLVED DLNDIIMNVC GKALVLMINE KREMNLLMGN
     TPEERYQYFE NEYSSTGKAF EEIKDKFPVI YIDLKNSINS YLKLVSQIMK DFKKDYSLLV
     ERKIIEEHST ISTMKIKGDL HNGKAVIEIT TNKSKLIYKP KSLSNDVFFN NFLKYMDSFF
     IKEGKSTKYK ENFYLVNTLD MKTYGWVEYV DKKPINSFEE ARNYYRKIGV LLSVAYTLNL
     TDLHFENVIS QGENPCIIDL ETMFNMPMFV KDYKNESRNI INGKIMDSVV STGMLPVLGI
     DSLFGGDPSG ILGGTFSKEE RVIINPFRDD IKFQKIVVRS VFKDHIPFFN NNNEKRYCKP
     KDYVNDIIKG FEKTYKIIVK NKEKILGFLK KESSSVTCRI LFRNTMEYSV LLNAAKSPVY
     SNKREEIFEK LSTFNRGLGN DIIKSEISQI NTLSIPYFNC QVDSNLIKNM DGETIFEHTL
     TPFKCFLSKY RRLCVDDMEQ QVKLIRFSIQ SQEQLFKDGE QFSLYKKQKG SQEDLLIAIN
     ELSSILENNA YIGTSDDTIN WMSLGIADND QILFESLEND IYKGISGIGL ALLEYYEFYP
     NINTKKILKL IYKNISKDFI NTNNEPQNYG FYVGLIGEYS FLRKYEKVFH KTSSCNILKN
     ILKDFTPEKC QTILPSDDVI AGEAGIIIYI SNLNNYLEYR DEIDILLKSL SNKIKLKESI
     ASYAHGNSGI ATAFVHGYKV TKNEKYLKIF HELWNLENSS KLRRGWTDSR KVDSSYSSQW
     CHGASGQAIA RMEWITVNKT ARFLSNSELI KVKKELGELI DILKKEGMYT DNFCLCHGIL
     GNLLILNTYQ ENFDNKNINL KNEILNNYYS VCNYGLNKGW ICGLGTEFYS YGLMTGISGI
     LYGLIRQVKQ KNNFGVLMPY VD