LCN6_MACMU
ID LCN6_MACMU Reviewed; 180 AA.
AC P62503; Q71SF5;
DT 19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=Epididymal-specific lipocalin-6;
DE Flags: Precursor;
GN Name=LCN6;
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Epididymis;
RX PubMed=14617364; DOI=10.1186/1477-7827-1-112;
RA Hamil K.G., Liu Q., Sivashanmugam P., Anbalagan M., Yenugu S.,
RA Soundararajan R., Grossman G., Rao A.J., Birse C.E., Ruben S.M.,
RA Richardson R.T., Zhang Y.L., O'Rand M.G., Petrusz P., French F.S.,
RA Hall S.H.;
RT "LCN6, a novel human epididymal lipocalin.";
RL Reprod. Biol. Endocrinol. 1:112-112(2003).
CC -!- FUNCTION: May play a role in male fertility.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- SIMILARITY: Belongs to the calycin superfamily. Lipocalin family.
CC {ECO:0000305}.
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DR EMBL; AF303085; AAQ14495.1; -; mRNA.
DR RefSeq; NP_001028003.1; NM_001032831.1.
DR AlphaFoldDB; P62503; -.
DR SMR; P62503; -.
DR STRING; 9544.ENSMMUP00000024683; -.
DR GeneID; 574148; -.
DR KEGG; mcc:574148; -.
DR CTD; 158062; -.
DR eggNOG; ENOG502T76S; Eukaryota.
DR HOGENOM; CLU_1622859_0_0_1; -.
DR InParanoid; P62503; -.
DR OMA; VMVTLTP; -.
DR OrthoDB; 1307977at2759; -.
DR TreeFam; TF353074; -.
DR Proteomes; UP000006718; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0036094; F:small molecule binding; IEA:InterPro.
DR GO; GO:0007338; P:single fertilization; IEA:UniProtKB-KW.
DR Gene3D; 2.40.128.20; -; 1.
DR InterPro; IPR012674; Calycin.
DR InterPro; IPR002345; Lipocalin.
DR InterPro; IPR022272; Lipocalin_CS.
DR InterPro; IPR000566; Lipocln_cytosolic_FA-bd_dom.
DR PANTHER; PTHR11430; PTHR11430; 1.
DR Pfam; PF00061; Lipocalin; 1.
DR SUPFAM; SSF50814; SSF50814; 1.
DR PROSITE; PS00213; LIPOCALIN; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Fertilization; Reference proteome; Secreted; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..180
FT /note="Epididymal-specific lipocalin-6"
FT /id="PRO_0000017915"
FT DISULFID 81..174
FT /evidence="ECO:0000250"
SQ SEQUENCE 180 AA; 19950 MW; 8F9FAECE3345104C CRC64;
MGGLLLAALL ALVAVPRAQA MWLGRLDPKQ LLGPWYVLAV ASREKSFAVE KDMKNVAGVV
VTLTPENNLR LLSSQHGLQG CSQSVTELLK RNSGWVFENP SIGVLELRVL ATNFRDYAII
FTQLEFGDEP FNTVELYSRR EAASQEAMGL FTKWSRGLGF LSQQQAQLQK DLTCAHKILS