ID   LCNDL_LACLA             Reviewed;         473 AA.
AC   Q9CJB7;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Lactococcin A secretion protein LcnD-like;
GN   Name=lcnD; OrderedLocusNames=LL0080; ORFNames=L84721;
OS   Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Lactococcus.
OX   NCBI_TaxID=272623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IL1403;
RX   PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA   Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA   Ehrlich S.D., Sorokin A.;
RT   "The complete genome sequence of the lactic acid bacterium Lactococcus
RT   lactis ssp. lactis IL1403.";
RL   Genome Res. 11:731-753(2001).
CC   -!- FUNCTION: Involved in the secretion of a lactococcin. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Single-pass type II membrane
CC       protein.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000305}.
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DR   EMBL; AE005176; AAK04178.1; -; Genomic_DNA.
DR   PIR; H86634; H86634.
DR   RefSeq; NP_266236.1; NC_002662.1.
DR   RefSeq; WP_010905095.1; NC_002662.1.
DR   AlphaFoldDB; Q9CJB7; -.
DR   SMR; Q9CJB7; -.
DR   STRING; 272623.L84721; -.
DR   PaxDb; Q9CJB7; -.
DR   EnsemblBacteria; AAK04178; AAK04178; L84721.
DR   KEGG; lla:L84721; -.
DR   PATRIC; fig|272623.7.peg.89; -.
DR   eggNOG; COG0845; Bacteria.
DR   HOGENOM; CLU_047946_0_0_9; -.
DR   OMA; HINDEYS; -.
DR   Proteomes; UP000002196; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043213; P:bacteriocin transport; IEA:UniProtKB-KW.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   InterPro; IPR005696; MesE/LcnD.
DR   InterPro; IPR006144; Secretion_HlyD_CS.
DR   TIGRFAMs; TIGR01000; bacteriocin_acc; 1.
DR   PROSITE; PS00543; HLYD_FAMILY; 1.
PE   3: Inferred from homology;
KW   Bacteriocin transport; Cell membrane; Membrane; Protein transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..473
FT                   /note="Lactococcin A secretion protein LcnD-like"
FT                   /id="PRO_0000201880"
FT   TOPO_DOM        1..21
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        22..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        45..473
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   473 AA;  52514 MW;  F606FBC90E354A0F CRC64;
     MFDKKLLESS ELYDKRYRNF STLIILPLFI LLVGGVIFTF FAHKELTVIS TGSIEPTKIV
     AKIQSTNANP IIENNLKEGK VVKENSLLLK YNGTPEQTQL SELLTQKKQV LDKKAQLDLL
     QKSLTNEKNE FPTTDSFGYE KSFENYESQV KSLEATIQKS NQAVEDQNKS TESQKQAIQN
     QVATLQQAIQ NYSEIENAVS SGGGVSQDNP YLSQYNSYQA QQATLEADLK NQKNPDETAK
     QATKSQEESL KSQFLSGLAS SKDSLKSQIQ SFNVQESSLT GSNAYDNSQS SQILTLKTQA
     LSASNKEMTD LNSTLTDLET KISLQKQDDQ YSQVFAEQTG VLHVLPDILG MKKIPIGTPI
     AEIYPLLKAE TQVNLTSYIP STQISGMKVG QKVRFTVQQN LPKPEILTGI IKQIDSAPTA
     FKEGNAYKVS ATTAINAKDL PNIRYGLQGK TVTIIGKKTY FNYFLDKIMG RTS