ID   LCRD_YERPS              Reviewed;         704 AA.
AC   P69956; P31487; Q56976; Q663K6;
DT   04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Low calcium response locus protein D;
GN   Name=lcrD; OrderedLocusNames=pYV0060;
OS   Yersinia pseudotuberculosis serotype I (strain IP32953).
OG   Plasmid pIB1, and Plasmid pYV.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=273123;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=YPIII / Serotype O:3; PLASMID=pIB1;
RA   Bergman T., Forsberg A., Backman A., Wolf-Watz H.;
RT   "The LcrD protein of Yersinia pseudotuberculosis belongs to a novel protein
RT   family involved in surface presentation of virulence determinants.";
RL   Submitted (NOV-1992) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IP32953; PLASMID=pYV;
RX   PubMed=15358858; DOI=10.1073/pnas.0404012101;
RA   Chain P.S.G., Carniel E., Larimer F.W., Lamerdin J., Stoutland P.O.,
RA   Regala W.M., Georgescu A.M., Vergez L.M., Land M.L., Motin V.L.,
RA   Brubaker R.R., Fowler J., Hinnebusch J., Marceau M., Medigue C.,
RA   Simonet M., Chenal-Francisque V., Souza B., Dacheux D., Elliott J.M.,
RA   Derbise A., Hauser L.J., Garcia E.;
RT   "Insights into the evolution of Yersinia pestis through whole-genome
RT   comparison with Yersinia pseudotuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:13826-13831(2004).
CC   -!- FUNCTION: Could be involved in the secretion of the yop virulence
CC       proteins.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC       pore) family. {ECO:0000305}.
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DR   EMBL; M96850; AAA27647.1; -; Genomic_DNA.
DR   EMBL; BX936399; CAF25403.1; -; Genomic_DNA.
DR   RefSeq; WP_002212971.1; NZ_CP009711.1.
DR   AlphaFoldDB; P69956; -.
DR   SMR; P69956; -.
DR   EnsemblBacteria; CAF25403; CAF25403; pYV0060.
DR   GeneID; 66841114; -.
DR   KEGG; ypo:BZ17_4273; -.
DR   KEGG; yps:pYV0060; -.
DR   PATRIC; fig|273123.14.peg.4509; -.
DR   OMA; PQFIGLQ; -.
DR   Proteomes; UP000001011; Plasmid pYV.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   Gene3D; 1.10.8.540; -; 1.
DR   Gene3D; 3.40.30.60; -; 1.
DR   Gene3D; 3.40.50.12790; -; 1.
DR   InterPro; IPR042194; FHIPEP_1.
DR   InterPro; IPR042193; FHIPEP_3.
DR   InterPro; IPR042196; FHIPEP_4.
DR   InterPro; IPR025505; FHIPEP_CS.
DR   InterPro; IPR001712; T3SS_FHIPEP.
DR   InterPro; IPR006302; T3SS_HrcV.
DR   PANTHER; PTHR30161; PTHR30161; 1.
DR   Pfam; PF00771; FHIPEP; 1.
DR   PIRSF; PIRSF005419; FlhA; 1.
DR   PRINTS; PR00949; TYPE3IMAPROT.
DR   TIGRFAMs; TIGR01399; hrcV; 1.
DR   PROSITE; PS00994; FHIPEP; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Plasmid; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport; Virulence.
FT   CHAIN           1..704
FT                   /note="Low calcium response locus protein D"
FT                   /id="PRO_0000190031"
FT   TRANSMEM        18..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        42..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        108..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        200..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        235..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        278..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        304..320
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   704 AA;  77802 MW;  21B25E2486910B56 CRC64;
     MNPHDLEWLN RIGERKDIML AVLLLAVVFM MVLPLPPLVL DILIAVNMTI SVVLLMIAIY
     INSPLQFSAF PAVLLVTTLF RLALSVSTTR MILLQADAGQ IVYTFGNFVV GGNLIVGIVI
     FLIITIVQFL VITKGSERVA EVSARFSLDA MPGKQMSIDG DMRAGVIDVN EARERRATIE
     KESQMFGSMD GAMKFVKGDA IAGLIIIFVN ILGGVTIGVT QKGLAAAEAL QLYSILTVGD
     GMVSQVPALL IAITAGIIVT RVSSEDSSDL GSDIGKQVVA QPKAMLIGGV LLLLFGLIPG
     FPTVTFLILA LLVGCGGYML SRKQSRNDEA NQDLQSILTS GSGAPAARTK AKTSGANKGR
     LGEQEAFAMT VPLLIDVDSS QQEALEAIAL NDELVRVRRA LYLDLGVPFP GIHLRFNEGM
     GEGEYIISLQ EVPVARGELK AGYLLVRESV SQLELLGIPY EKGEHLLPDQ EAFWVSVEYE
     ERLEKSQLEF FSHSQVLTWH LSHVLREYAE DFIGIQETRY LLEQMEGGYG ELIKEVQRIV
     PLQRMTEILQ RLVGEDISIR NMRSILEAMV EWGQKEKDVV QLTEYIRSSL KRYICYKYAN
     GNNILPAYLF DQEVEEKIRS GVRQTSAGSY LALEPAVTES LLEQVRKTIG DLSQIQSKPV
     LIVSMDIRRY VRKLIESEYY GLPVLSYQEL TQQINIQPLG RICL