ID   LCRP_PETMA              Reviewed;          19 AA.
AC   Q10996;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Corticostatin-related peptide LCRP;
OS   Petromyzon marinus (Sea lamprey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Cyclostomata;
OC   Hyperoartia; Petromyzontiformes; Petromyzontidae; Petromyzon.
OX   NCBI_TaxID=7757;
RN   [1]
RP   PROTEIN SEQUENCE, AND MASS SPECTROMETRY.
RC   TISSUE=Skin;
RX   PubMed=8759287; DOI=10.1016/0305-0491(95)02132-9;
RA   Conlon J.M., Sower S.A.;
RT   "Isolation of a peptide structurally related to mammalian corticostatins
RT   from the lamprey Petromyzon marinus.";
RL   Comp. Biochem. Physiol. 114B:133-137(1996).
CC   -!- FUNCTION: May have microbicidal activities. May inhibit corticotropin
CC       (ACTH) stimulated steroidogenesis and the microbial actions of the
CC       corticostatins.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- MASS SPECTROMETRY: Mass=2201; Mass_error=0.4; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:8759287};
CC   -!- SIMILARITY: Belongs to the alpha-defensin family. {ECO:0000305}.
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DR   AlphaFoldDB; Q10996; -.
DR   Ensembl; ENSPMAT00000011096; ENSPMAP00000011050; ENSPMAG00000010069.
DR   HOGENOM; CLU_3430684_0_0_1; -.
DR   Proteomes; UP000245300; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Defensin; Direct protein sequencing;
KW   Disulfide bond; Reference proteome; Secreted.
FT   PEPTIDE         1..19
FT                   /note="Corticostatin-related peptide LCRP"
FT                   /id="PRO_0000043635"
FT   DISULFID        1..18
FT                   /evidence="ECO:0000250"
FT   DISULFID        3..9
FT                   /evidence="ECO:0000250"
FT   DISULFID        8..17
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   19 AA;  2209 MW;  8D9CEDC71A199AE5 CRC64;
     CPCGRRRCCV RGLNVYCCF