ID   LCRV_YERPP              Reviewed;         324 AA.
AC   A4TSQ1; O68697; P21206; Q9L9Q7; Q9L9Q8;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Virulence-associated V antigen;
DE   AltName: Full=Low calcium response locus protein V;
GN   Name=lcrV; Synonyms=icrV; OrderedLocusNames=YPDSF_3986;
OS   Yersinia pestis (strain Pestoides F).
OG   Plasmid pCD.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=386656;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10747136; DOI=10.1128/jcm.38.4.1516-1519.2000;
RA   Adair D.M., Worsham P.L., Hill K.K., Klevytska A.M., Jackson P.J.,
RA   Friedlander A.M., Keim P.;
RT   "Diversity in a variable-number tandem repeat from Yersinia pestis.";
RL   J. Clin. Microbiol. 38:1516-1519(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pestoides F;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Di Bartolo G., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Worsham P., Chu M., Bearden S., Garcia E.,
RA   Richardson P.;
RT   "Complete sequence of plasmid pCD of Yersinia pestis Pestoides F.";
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Possibly involved in calcium regulation of YOP expression,
CC       which includes the export process. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
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DR   EMBL; AF167309; AAF64076.1; -; Genomic_DNA.
DR   EMBL; CP000669; ABP42325.1; -; Genomic_DNA.
DR   RefSeq; WP_011171995.1; NZ_CP009713.1.
DR   AlphaFoldDB; A4TSQ1; -.
DR   SMR; A4TSQ1; -.
DR   KEGG; ypp:YPDSF_3986; -.
DR   PATRIC; fig|386656.14.peg.4354; -.
DR   OMA; EKMSQTT; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005413; LowCa_resp_V_Ag.
DR   InterPro; IPR036139; Vir_assoc_V_ag_sf.
DR   Pfam; PF04792; LcrV; 1.
DR   PRINTS; PR01592; LCRVANTIGEN.
DR   SUPFAM; SSF103388; SSF103388; 1.
PE   3: Inferred from homology;
KW   Plasmid; Secreted; Virulence.
FT   CHAIN           1..324
FT                   /note="Virulence-associated V antigen"
FT                   /id="PRO_0000293453"
SQ   SEQUENCE   324 AA;  37124 MW;  5810C1A2E169AE5A CRC64;
     MIRAYEQNPQ HFIEDLEKVR VEQLTGHGSS VLEELVQLVK DKNIDISIKY DPRKDSEVFA
     NRVITDDIEL LKKILAYFLP EDAILKGGHY DNQLQNGIKR VKEFLESSPN TQWELRAFMA
     VMHFSLTADR IDDDILKVIV DSMNHHGDAR SKLREELAEL TAELKIYSVI QAEINKHLSS
     SGTINIHDKS INLMDKNLYG YTDEEIFKAS AEYKILEKMP QTTIQVDGSE KKIVSIKDFL
     GSENKRTGAL GNLKNSYSYN KDNNELSHFA TTCSDKSRPL NDLVSQKTTQ LSDITSRFNS
     AIEALNRFIQ KYDSVMQRLL DDTR