LCV1_ARATH
ID LCV1_ARATH Reviewed; 256 AA.
AC Q8VY49; Q9SL68;
DT 04-FEB-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Protein LIKE COV 1 {ECO:0000303|PubMed:12668628};
GN Name=LCV1 {ECO:0000303|PubMed:12668628};
GN OrderedLocusNames=At2g20130 {ECO:0000312|Araport:AT2G20130};
GN ORFNames=T2G17.7 {ECO:0000312|EMBL:AAD24400.2};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:AAL62439.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP TISSUE SPECIFICITY, GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Landsberg erecta;
RX PubMed=12668628; DOI=10.1242/dev.00441;
RA Parker G., Schofield R., Sundberg B., Turner S.;
RT "Isolation of COV1, a gene involved in the regulation of vascular
RT patterning in the stem of Arabidopsis.";
RL Development 130:2139-2148(2003).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- TISSUE SPECIFICITY: Expressed at low levels in flowers, stems, roots
CC and leaves. {ECO:0000269|PubMed:12668628}.
CC -!- SIMILARITY: Belongs to the plant COV1 protein family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC006081; AAD24400.2; -; Genomic_DNA.
DR EMBL; CP002685; AEC06969.1; -; Genomic_DNA.
DR EMBL; AY072447; AAL62439.1; -; mRNA.
DR EMBL; AY128911; AAM91311.1; -; mRNA.
DR EMBL; AY084942; AAM61503.1; -; mRNA.
DR PIR; D84585; D84585.
DR RefSeq; NP_565465.1; NM_127571.3.
DR AlphaFoldDB; Q8VY49; -.
DR IntAct; Q8VY49; 23.
DR STRING; 3702.AT2G20130.1; -.
DR PaxDb; Q8VY49; -.
DR PRIDE; Q8VY49; -.
DR ProteomicsDB; 238411; -.
DR EnsemblPlants; AT2G20130.1; AT2G20130.1; AT2G20130.
DR GeneID; 816532; -.
DR Gramene; AT2G20130.1; AT2G20130.1; AT2G20130.
DR KEGG; ath:AT2G20130; -.
DR Araport; AT2G20130; -.
DR TAIR; locus:2061654; AT2G20130.
DR eggNOG; ENOG502QPUG; Eukaryota.
DR HOGENOM; CLU_068050_0_1_1; -.
DR InParanoid; Q8VY49; -.
DR OMA; NSECEPF; -.
DR OrthoDB; 1076488at2759; -.
DR PhylomeDB; Q8VY49; -.
DR PRO; PR:Q8VY49; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8VY49; baseline and differential.
DR Genevisible; Q8VY49; AT.
DR GO; GO:0005794; C:Golgi apparatus; HDA:TAIR.
DR GO; GO:0000137; C:Golgi cis cisterna; HDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0010222; P:stem vascular tissue pattern formation; IBA:GO_Central.
DR InterPro; IPR007462; COV1-like.
DR PANTHER; PTHR31876; PTHR31876; 1.
DR Pfam; PF04367; DUF502; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..256
FT /note="Protein LIKE COV 1"
FT /id="PRO_0000431899"
FT TOPO_DOM 1..60
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 61..81
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TOPO_DOM 82..93
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 94..114
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TOPO_DOM 115..256
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 256 AA; 28379 MW; 4A4BD808A297F44C CRC64;
MANRERDREL LIPVADFGDK DDGSSSKPSS SSSASSSHQS GHETLSLFIR GWASKKFMTG
CVILLPIAVT FYTTWWFIHF VDGFFSPIYA LLGINIFGFG FLTSIAFIFL VGVFMSSWLG
ASVLNLGEWF IKRMPFVRHI YNASKQISTA ISPDQNTQAF KEVAIIRHPR VGEYAFGFIT
STVVLQNYPT EEELCCVYVP TNHLYIGDIL LVNSNDVIRP NLSVREGIEI VVSGGMSMPQ
ILSTLDKPLA SIGNES
