ID   LCV3_ARATH              Reviewed;         274 AA.
AC   F4IQJ6; Q9ZPX6;
DT   04-FEB-2015, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Protein LIKE COV 3 {ECO:0000303|PubMed:12668628};
GN   Name=LCV3 {ECO:0000303|PubMed:12668628};
GN   OrderedLocusNames=At2g18460 {ECO:0000312|Araport:AT2G18460};
GN   ORFNames=T30D6.3 {ECO:0000312|EMBL:AAD15492.1};
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   GENE FAMILY, AND NOMENCLATURE.
RC   STRAIN=cv. Landsberg erecta;
RX   PubMed=12668628; DOI=10.1242/dev.00441;
RA   Parker G., Schofield R., Sundberg B., Turner S.;
RT   "Isolation of COV1, a gene involved in the regulation of vascular
RT   patterning in the stem of Arabidopsis.";
RL   Development 130:2139-2148(2003).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the plant COV1 protein family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD15492.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AC006439; AAD15492.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002685; AEC06770.1; -; Genomic_DNA.
DR   EMBL; DQ069818; -; NOT_ANNOTATED_CDS; mRNA.
DR   PIR; E84564; E84564.
DR   RefSeq; NP_179436.3; NM_127402.4.
DR   AlphaFoldDB; F4IQJ6; -.
DR   PaxDb; F4IQJ6; -.
DR   PRIDE; F4IQJ6; -.
DR   ProteomicsDB; 250772; -.
DR   EnsemblPlants; AT2G18460.1; AT2G18460.1; AT2G18460.
DR   GeneID; 816360; -.
DR   Gramene; AT2G18460.1; AT2G18460.1; AT2G18460.
DR   KEGG; ath:AT2G18460; -.
DR   Araport; AT2G18460; -.
DR   TAIR; locus:2062131; AT2G18460.
DR   eggNOG; ENOG502QRSM; Eukaryota.
DR   HOGENOM; CLU_068050_0_1_1; -.
DR   InParanoid; F4IQJ6; -.
DR   OMA; ACVYVPT; -.
DR   OrthoDB; 1076488at2759; -.
DR   PRO; PR:F4IQJ6; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; F4IQJ6; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR007462; COV1-like.
DR   PANTHER; PTHR31876; PTHR31876; 1.
DR   Pfam; PF04367; DUF502; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..274
FT                   /note="Protein LIKE COV 3"
FT                   /id="PRO_0000431901"
FT   TOPO_DOM        1..60
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        61..81
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        82..93
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        94..114
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        115..274
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   274 AA;  30454 MW;  B739A5C604BDF333 CRC64;
     METRERDLER LIPMHKSGAS PRDVVLSVPP SPLASPIHVA GKEAIYKVIR SWASKKFMTG
     CVILLPIAVT FYFTWWFIHF VDGFFSPIYT HLGINMFGLG FVTSITFIFM VGVFMSSWLG
     ASVLSIGEWF IKKMPLVSYI YSASKQISGA ISPDQSSGAF KEVAIIRHPH MGEYAFGFIT
     STVILRGRAG GEELCCVYVP TNHLYLGDIF LISSKDIIRP NLSVREGIEI VISGGMSIPH
     MLTTLDSETI HRMLESFGIL EFGDVCLSLV LAWT