ID   LDB18_YEAST             Reviewed;         179 AA.
AC   Q07887; D6VXV9;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Protein LDB18;
DE   AltName: Full=Low dye-binding protein 18;
GN   Name=LDB18; OrderedLocusNames=YLL049W;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169871;
RA   Johnston M., Hillier L.W., Riles L., Albermann K., Andre B., Ansorge W.,
RA   Benes V., Brueckner M., Delius H., Dubois E., Duesterhoeft A.,
RA   Entian K.-D., Floeth M., Goffeau A., Hebling U., Heumann K.,
RA   Heuss-Neitzel D., Hilbert H., Hilger F., Kleine K., Koetter P., Louis E.J.,
RA   Messenguy F., Mewes H.-W., Miosga T., Moestl D., Mueller-Auer S.,
RA   Nentwich U., Obermaier B., Piravandi E., Pohl T.M., Portetelle D.,
RA   Purnelle B., Rechmann S., Rieger M., Rinke M., Rose M., Scharfe M.,
RA   Scherens B., Scholler P., Schwager C., Schwarz S., Underwood A.P.,
RA   Urrestarazu L.A., Vandenbol M., Verhasselt P., Vierendeels F., Voet M.,
RA   Volckaert G., Voss H., Wambutt R., Wedler E., Wedler H., Zimmermann F.K.,
RA   Zollner A., Hani J., Hoheisel J.D.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.";
RL   Nature 387:87-90(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   FUNCTION.
RX   PubMed=15993632; DOI=10.1016/j.fgb.2005.05.002;
RA   Corbacho I., Olivero I., Hernandez L.M.;
RT   "A genome-wide screen for Saccharomyces cerevisiae nonessential genes
RT   involved in mannosyl phosphate transfer to mannoprotein-linked
RT   oligosaccharides.";
RL   Fungal Genet. Biol. 42:773-790(2005).
CC   -!- FUNCTION: May be involved in protein-linked oligosaccharide
CC       phosphorylation since the deletion reduces the negative charge of the
CC       cell surface. {ECO:0000269|PubMed:15993632}.
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DR   EMBL; Z73154; CAA97501.1; -; Genomic_DNA.
DR   EMBL; BK006945; DAA09275.1; -; Genomic_DNA.
DR   PIR; S64801; S64801.
DR   RefSeq; NP_013051.1; NM_001181869.1.
DR   AlphaFoldDB; Q07887; -.
DR   SMR; Q07887; -.
DR   BioGRID; 31266; 456.
DR   ComplexPortal; CPX-1805; Dynactin.
DR   DIP; DIP-1932N; -.
DR   IntAct; Q07887; 8.
DR   MINT; Q07887; -.
DR   STRING; 4932.YLL049W; -.
DR   PaxDb; Q07887; -.
DR   PRIDE; Q07887; -.
DR   EnsemblFungi; YLL049W_mRNA; YLL049W; YLL049W.
DR   GeneID; 850677; -.
DR   KEGG; sce:YLL049W; -.
DR   SGD; S000003972; LDB18.
DR   VEuPathDB; FungiDB:YLL049W; -.
DR   eggNOG; ENOG502SBP6; Eukaryota.
DR   HOGENOM; CLU_1590434_0_0_1; -.
DR   InParanoid; Q07887; -.
DR   OMA; VDNCNIM; -.
DR   BioCyc; YEAST:G3O-32148-MON; -.
DR   PRO; PR:Q07887; -.
DR   Proteomes; UP000002311; Chromosome XII.
DR   RNAct; Q07887; protein.
DR   GO; GO:0015629; C:actin cytoskeleton; IC:ComplexPortal.
DR   GO; GO:0005869; C:dynactin complex; IDA:SGD.
DR   GO; GO:0030048; P:actin filament-based movement; IC:ComplexPortal.
DR   GO; GO:0000132; P:establishment of mitotic spindle orientation; IMP:SGD.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..179
FT                   /note="Protein LDB18"
FT                   /id="PRO_0000240386"
SQ   SEQUENCE   179 AA;  20847 MW;  F3932244CFC84895 CRC64;
     MPGLKLVEAL EYRCDRLERL IGAGYSANSD VSVQLDELYN QLHRLYFQGL KYSQDLLQLF
     NTFMAEDIEN VGAPDDICIF ASCFDDIYTL YSAFDELNSQ YMEFCQISKS SLDQISFKDA
     NIETKQLKKL PELVDNCNIM ILRSIAILNR FIDWNIEVNG FFQFQKKRLL NLQKVIYST