ID   LDH_PLAFA               Reviewed;          42 AA.
AC   P13774;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=L-lactate dehydrogenase;
DE            EC=1.1.1.27;
DE   AltName: Full=LDH-P;
DE   Flags: Fragment;
OS   Plasmodium falciparum.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=5833;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3892292; DOI=10.1016/0166-6851(85)90122-7;
RA   Simmons D.L., Hyde J.E., Mackay M., Goman M., Scaife J.;
RT   "Cloning studies on the gene coding for L-(+)-lactate dehydrogenase of
RT   Plasmodium falciparum.";
RL   Mol. Biochem. Parasitol. 15:231-243(1985).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-lactate + NAD(+) = H(+) + NADH + pyruvate;
CC         Xref=Rhea:RHEA:23444, ChEBI:CHEBI:15361, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16651, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.27;
CC         Evidence={ECO:0000255|PROSITE-ProRule:PRU10002};
CC   -!- PATHWAY: Fermentation; pyruvate fermentation to lactate; (S)-lactate
CC       from pyruvate: step 1/1.
CC   -!- SUBUNIT: Homotetramer.
CC   -!- SIMILARITY: Belongs to the LDH/MDH superfamily. LDH family.
CC       {ECO:0000305}.
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DR   EMBL; M14818; AAA29634.1; -; Genomic_DNA.
DR   AlphaFoldDB; P13774; -.
DR   SABIO-RK; P13774; -.
DR   UniPathway; UPA00554; UER00611.
DR   GO; GO:0004459; F:L-lactate dehydrogenase activity; IEA:UniProtKB-EC.
PE   3: Inferred from homology;
KW   NAD; Oxidoreductase.
FT   CHAIN           <1..>42
FT                   /note="L-lactate dehydrogenase"
FT                   /id="PRO_0000168496"
FT   REGION          15..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT   NON_TER         42
SQ   SEQUENCE   42 AA;  4955 MW;  7FE28FDC341F474B CRC64;
     LLVYDNLLLN DKNEMNKDSS YDKKTNALDN YKNDSTIDME KK