ARD15_CAEEL
ID ARD15_CAEEL Reviewed; 374 AA.
AC P30647; C9IY19; C9IY20;
DT 01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 2.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Arrestin domain-containing protein 15;
GN Name=arrd-15; ORFNames=ZK643.1;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=1538779; DOI=10.1038/356037a0;
RA Sulston J., Du Z., Thomas K., Wilson R., Hillier L., Staden R.,
RA Halloran N., Green P., Thierry-Mieg J., Qiu L., Dear S., Coulson A.,
RA Craxton M., Durbin R., Berks M., Metzstein M., Hawkins T., Ainscough R.,
RA Waterston R.;
RT "The C. elegans genome sequencing project: a beginning.";
RL Nature 356:37-41(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=a;
CC IsoId=P30647-1; Sequence=Displayed;
CC Name=b;
CC IsoId=P30647-2; Sequence=VSP_039806;
CC -!- SIMILARITY: Belongs to the arrestin family. {ECO:0000305}.
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DR EMBL; Z11126; CBG22758.1; -; Genomic_DNA.
DR EMBL; Z11126; CBG22759.1; -; Genomic_DNA.
DR PIR; S23239; S23239.
DR RefSeq; NP_001254970.1; NM_001268041.1. [P30647-1]
DR RefSeq; NP_001254971.1; NM_001268042.1. [P30647-2]
DR AlphaFoldDB; P30647; -.
DR SMR; P30647; -.
DR STRING; 6239.ZK643.1a; -.
DR EPD; P30647; -.
DR PaxDb; P30647; -.
DR EnsemblMetazoa; ZK643.1a.1; ZK643.1a.1; WBGene00014033. [P30647-1]
DR EnsemblMetazoa; ZK643.1b.1; ZK643.1b.1; WBGene00014033. [P30647-2]
DR GeneID; 191372; -.
DR UCSC; ZK643.1; c. elegans. [P30647-1]
DR CTD; 191372; -.
DR WormBase; ZK643.1a; CE44158; WBGene00014033; arrd-15. [P30647-1]
DR WormBase; ZK643.1b; CE44174; WBGene00014033; arrd-15. [P30647-2]
DR eggNOG; KOG3780; Eukaryota.
DR HOGENOM; CLU_809506_0_0_1; -.
DR InParanoid; P30647; -.
DR OMA; LPGIECE; -.
DR OrthoDB; 817924at2759; -.
DR PhylomeDB; P30647; -.
DR PRO; PR:P30647; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00014033; Expressed in larva and 3 other tissues.
DR ExpressionAtlas; P30647; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; HDA:WormBase.
DR GO; GO:0055120; C:striated muscle dense body; HDA:WormBase.
DR GO; GO:0015031; P:protein transport; IBA:GO_Central.
DR Gene3D; 2.60.40.640; -; 2.
DR InterPro; IPR014752; Arrestin-like_C.
DR InterPro; IPR011021; Arrestin-like_N.
DR InterPro; IPR011022; Arrestin_C-like.
DR InterPro; IPR014756; Ig_E-set.
DR Pfam; PF02752; Arrestin_C; 1.
DR Pfam; PF00339; Arrestin_N; 1.
DR SMART; SM01017; Arrestin_C; 1.
DR SUPFAM; SSF81296; SSF81296; 2.
PE 3: Inferred from homology;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..374
FT /note="Arrestin domain-containing protein 15"
FT /id="PRO_0000065532"
FT REGION 344..374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 350..368
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..32
FT /note="Missing (in isoform b)"
FT /evidence="ECO:0000305"
FT /id="VSP_039806"
SQ SEQUENCE 374 AA; 42131 MW; 319A49D9E3AFA6D3 CRC64;
MPEVSNGRRP SVATFLRQFA STIIPLVNVK QSMPTTQINI VLAEPRCMAG EFFNAKVLLD
SSDPDTVVHS FCAEIKGIGR TGWVNIHTDK IFETEKTYID TQVQLCDSGT CLPVGKHQFP
VQIRIPLNCP SSYESQFGSI RYQMKVELRA STDQASCSEV FPLVILTRSF FDDVPLNAMS
PIDFKDEVDF TCCTLPFGCV SLNMSLTRTA FRIGESIEAV VTINNRTRKG LKEVALQLIM
KTQFEARSRY EHVNEKKLAE QLIEMVPLGA VKSRCRMEFE KCLLRIPDAA PPTQNYNRGA
GESSIIAIHY VLKLTALPGI ECEIPLIVTS CGYMDPHKQA AFQHHLNRSK AKVSKTEQQQ
RKTRNIVEEN PYFR