ID   ARD1_DICDI              Reviewed;         203 AA.
AC   P36416; Q552Y6; Q86H48;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   03-AUG-2022, entry version 111.
DE   RecName: Full=N-terminal acetyltransferase complex ARD1 subunit homolog;
DE            EC=2.3.1.-;
GN   Name=natA; Synonyms=ard1; ORFNames=DDB_G0275449;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=AX2;
RA   Mueller-Taubenberger A.;
RT   "N-terminal acetyltransferase complex subunit gene from Dictyostelium
RT   discoideum.";
RL   Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Seems to be involved in N-acetylation. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the acetyltransferase family. ARD1 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; U06453; AAA16510.1; -; mRNA.
DR   EMBL; AAFI02000013; EAL69475.2; -; Genomic_DNA.
DR   RefSeq; XP_643534.2; XM_638442.2.
DR   AlphaFoldDB; P36416; -.
DR   SMR; P36416; -.
DR   STRING; 44689.DDB0185212; -.
DR   PaxDb; P36416; -.
DR   EnsemblProtists; EAL69475; EAL69475; DDB_G0275449.
DR   GeneID; 8620116; -.
DR   KEGG; ddi:DDB_G0275449; -.
DR   dictyBase; DDB_G0275449; natA.
DR   eggNOG; KOG3235; Eukaryota.
DR   HOGENOM; CLU_013985_7_2_1; -.
DR   InParanoid; P36416; -.
DR   OMA; MSMQNAN; -.
DR   PhylomeDB; P36416; -.
DR   PRO; PR:P36416; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0031415; C:NatA complex; IBA:GO_Central.
DR   GO; GO:1990190; F:peptide-glutamate-N-acetyltransferase activity; IBA:GO_Central.
DR   GO; GO:1990189; F:peptide-serine-N-acetyltransferase activity; IBA:GO_Central.
DR   GO; GO:0006474; P:N-terminal protein amino acid acetylation; IEA:InterPro.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR045047; Ard1-like.
DR   InterPro; IPR000182; GNAT_dom.
DR   PANTHER; PTHR23091; PTHR23091; 1.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   2: Evidence at transcript level;
KW   Acyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..203
FT                   /note="N-terminal acetyltransferase complex ARD1 subunit
FT                   homolog"
FT                   /id="PRO_0000074530"
FT   DOMAIN          2..151
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00532"
FT   REGION          177..203
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   203 AA;  23415 MW;  501B6B46DFF0F146 CRC64;
     MVSIRPCQIG DLMSMQNANL TCLPENYQMK YYLYHFLTWP QTSFVAEDDK GNVVGYVLAK
     IDENEPKRGH ITSLAVLRSQ RKLGIATKLM KQAEVALLEV YDADCVSLHV RKSNRAAFSL
     YHEVLKFKID EIEKEYYGDK EDAYSMVLYL KPEVEEEKER EKQLEKINKA AKESIEAAKR
     ANEEPKPVSN VIHGKKKNVK KIE